Objective. The article considers the role of knowledge management in the library of a higher education institution in the modern conditions of the global information society. The process of implementing LibGuides as a new tool for systematization, analysis, preservation, transfer, actualization of knowledge, and access to it is highlighted. Methods. The study was conducted by using methods: analytical and review, analysis and synthesis, comparison of experience of the world’s university libraries, and statistical method. Results. The role of the library as an information institute in the context of the development of the knowledge society is shown. The experience of Sumy State University Library regarding the LibGuides project implementation, which contributes to the creation of new knowledge, its productive use, as well as the formation of information literacy and academic integrity of scientists, teachers, and students, is considered. Conclusions. University libraries play a significant role in the organization of knowledge management of all participants in the educational and scientific process. LibGuides are an effective tool in the practice of knowledge management, which includes the librarian's work with new technologies, generating new knowledge, and sharing knowledge without any geographical limitations.