Connective tissue nevi in children: Institutional experience and review

McCuaig, Catherine; Vera, Caridad; Kokta, Victor; Marcoux, Danielle; Hatami, Afshin; Thuraisingam, Thusanth; Marton, Dominique; Fortier-Riberdy, Geneviève; Powell, Julie

doi:10.1016/j.jaad.2012.01.036

Cited by 38 publications

(42 citation statements)

References 55 publications

(74 reference statements)

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“…There is no estimated incidence or prevalence of CTN. The lesions can be acquired or congenital, sporadic or inherited . They may be features of several syndromes, such as Buschke–Ollendorff syndrome , Proteus syndrome , tuberous sclerosis , or multiple endocrine neoplasia type 1 .…”

Section: Discussionmentioning

confidence: 99%

“…In 1980, Uitto et al first classified CTN. More recently, McCuaig et al proposed a new, modified classification, dividing CTN into acquired and inherited lesions and classifying them also according to the major component of the extracellular matrix: collagenoma if the major component is collagen, elastoma if it is elastin, and mucinous nevus in the case of proteoglycans.…”

Section: Discussionmentioning

confidence: 99%

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Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation

Downey

Requena

Bagué

et al. 2016

Pediatric Dermatology

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Connective tissue nevi are benign hamartomatous lesions in which one or several of the components of the dermis (collagen, elastin, glicosaminoglycans) show predominance or depletion. Recently, de Feraudy et al broadened the spectrum of connective tissue nevus, describing fibroblastic connective tissue nevus (FCTN), which is characterized by proliferation of CD34+ cells of fibroblastic and myofibroblastic lineage. Only solitary papules and nodules have been described. We present the first case of FCTN with multiple agminated lesions on the leg of an infant and the difficulties encountered in the differential diagnosis with dermatofibrosarcoma protuberans.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation

Downey

Requena

Bagué

et al. 2016

Pediatric Dermatology

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“…These lesions are very firm and contain deep sulci that resemble the brain, for which the lesion is named. Histology sections of CCTN show massively expanded dermis filled with thick collagen bundles (Figure 1d-f) (McCuaig et al 2012). Epidermal nevi (EN) can be non-syndromic or occur as part of several syndromes including PS (Happle 2010).…”

mentioning

confidence: 99%

AKT1 Gene Mutation Levels Are Correlated with the Type of Dermatologic Lesions in Patients with Proteus Syndrome

Lindhurst

Wang

Bloomhardt

et al. 2014

Journal of Investigative Dermatology

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“…Connective tissue nevi are dermal hamartomas characterized by an abnormal accumulation of collagen, elastin, or proteoglycans . Uitto et al first classified connective tissue nevi in 1980.…”

Section: Discussionmentioning

confidence: 99%

A New Variant of Connective Tissue Nevus with Elastorrhexis and Predilection for the Upper Chest

Chu

Goldbach

Wanat

et al. 2014

Pediatric Dermatology

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Localized changes in cutaneous elastic tissue often manifest with flesh-colored, hypopigmented, or yellow papules, plaques, and nodules. We present five children with clinically similar cobblestone plaques composed of multiple hypopigmented, nonfollicular, pinpoint papules located unilaterally over the upper chest. All lesions first appeared at birth or during early infancy. No associated extracutaneous abnormalities have been identified. Histopathology was remarkable for many, thick elastic fibers with elastorrhexis. We believe that these cases represent a distinct and unique variant of connective tissue nevi.

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Connective tissue nevi in children: Institutional experience and review

Cited by 38 publications

References 55 publications

Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation

Agminated Fibroblastic Conective Tissue Nevus: A New Clinical Presentation

AKT1 Gene Mutation Levels Are Correlated with the Type of Dermatologic Lesions in Patients with Proteus Syndrome

A New Variant of Connective Tissue Nevus with Elastorrhexis and Predilection for the Upper Chest

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