2013
DOI: 10.1016/j.jtv.2013.04.003
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Connective tissue ulcers

Abstract: Connective tissue disorders (CTD), which are often also termed collagen vascular diseases, include a number of related inflammatory conditions. Some of these diseases include rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis (scleroderma), localized scleroderma (morphea variants localized to the skin), Sjogren’s syndrome, dermatomyositis, polymyositis, and mixed connective tissue disease. In addition to the systemic manifestations of these diseases, there are a number of cutaneous features… Show more

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Cited by 28 publications
(21 citation statements)
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“…14 Hydrogel dressings have been shown to be effective in treating eschar. Hydrogels may be selected for patients for whom sharp surgical debridement is contraindicated.…”
Section: Dabiri Damstetter and Phillipsmentioning
confidence: 99%
“…14 Hydrogel dressings have been shown to be effective in treating eschar. Hydrogels may be selected for patients for whom sharp surgical debridement is contraindicated.…”
Section: Dabiri Damstetter and Phillipsmentioning
confidence: 99%
“…However, coexistent prothrombotic states such as antiphospholipid syndrome may also play a role in some patients (Figure 3) (16, 17). Typically, histologic examination of wounds in SLE shows a leukocytoclastic vasculitis with fibrinoid necrosis of the vessel wall and prominent polymorphonuclear cell infiltration.…”
Section: Leg Ulcers Associated With Systemic Lupus Erythematosusmentioning
confidence: 99%
“…It is important to recognize this etiology for leg ulceration since it has a high mortality. Treatment includes removal or stenting of unstable atheromatous plaques as well as initiation of statins(16). …”
Section: Differential Diagnosis Of Vasculitic Woundsmentioning
confidence: 99%
“…The mortality of cholesterol emboli syndrome is high. Treatment includes removal or stenting of unstable atheromatous plaques as well as initiation of statins (17). …”
Section: Occlusive Diseases Resulting In Ulcersmentioning
confidence: 99%
“…Histologic examination of wounds in SLE shows a leukocytoclastic vasculitis with fibrinoid necrosis of the vessel wall and prominent polymorphonuclear cell infiltration. Coexistent prothrombotic states such as antiphospholipid syndrome may also play a role in some patients (17, 18) and thromboocclusive histologic findings should prompt additional work up (5). Treatment of wounds in patients with SLE should focus on the management of the underlying autoimmune and inflammatory disease.…”
Section: Overview Of Vasculitic Woundsmentioning
confidence: 99%