Consanguineous matings in the Egyptian population.

Abstract

SUMMARY A total of 26 554 Egyptians was ascertained to study the incidence of consanguineous marriages. They were of different ages, different socioeconomic standards, and from different areas. There were 7646 from urban areas, 11 280 from suburban areas, and 7628 from rural areas.The incidence of consanguineous matings in the general population was found to be 28-96% with an average inbreeding coefficient of 0-010, which could be considered high. The highest incidence was that in the rural areas. First cousin marriages occurred more often than the other types of consanguinity.

Y-chromosome diversity characterizes the Gulf of Oman

“…A study performed within Sana'a City, Yemen revealed a incidence of consanguinity of 44.7%, with first-cousin marriages comprising 71.6%, and an average coefficient of inbreeding (the probability of an individual having two alleles identical by descent at a given locus) of 0.02442, 59 almost double that of the Egyptian population (0.01) 60 and four times that of the Turkish population (0.0064532). 61 Similar studies conducted in Qatar indicate a rate of consanguinity of 54.0% (first cousin marriages accounting for 34.8%) and a coefficient of inbreeding of 0.02706, 62 whereas comparable consanguinity values were observed in UAE (50.5%) 63 and Oman (35.9%).…”

The changing incidence and sites of colorectal cancer in the Israeli Arab population and their clinical implications

“…[33][34][35][36][37][38] They too emphasize the higher rates of consanguineous marriage in their communities and the finding of hereditary nonpolyposis CRC in a proportion of patients. 12,[38][39][40] The most complete published data is from the Kingdom of Jordan and confirms the higher risk for rectal cancer in their population as compared to SEER or Israeli data. 41 A Middle East Consortium monograph, comparing malignant diseases in 5 Middle Eastern populations, 1996-2002, is now being published by the National Cancer Institute (USA).…”

Prevalence of Consanguineous Marriages in South Sinai, Egypt

“…The mean inbreeding coefficient of the screened population in South Sinai was 0.0184. In previous studies the average inbreeding coefficient in the Egyptian population was found to be 0.010-0.0117 (Hafez et al, 1983;Mohamed, 1995). These figures are considered high compared with most Western societies, where the average inbreeding coefficient is usually less than 0.001 (Bittles, 2011).…”

“…Studies on the frequency of parental consanguinity in the Egyptian population have given figures ranging from 20.9 to 32.8% (Stevenson et al, 1966;Hafez et al, 1983;Mohamed, 1995;Mokhtar & Abdel-Fattah, 2001), except for Nubia in the south where consanguinity raes as high as 60-80% have been reported (Hussien, 1971;Badr, 1972). Consanguinity rates were found to be higher in rural than in urban settings (Hafez et al, 1983). The most common consanguineous marriages in Egypt occur between first cousins (50%), followed by first cousins once removed (15%), second cousins (15%) and other more distant relations (Hafez et al, 1983).…”

“…Consanguinity rates were found to be higher in rural than in urban settings (Hafez et al, 1983). The most common consanguineous marriages in Egypt occur between first cousins (50%), followed by first cousins once removed (15%), second cousins (15%) and other more distant relations (Hafez et al, 1983). The prevalence of consanguinity and rates of first cousin marriage vary widely within and between populations and communities, depending on ethnicity, religion, culture and geography.…”