Consanguinity related prenatal and postnatal mortality of the populations of seven Pakistani Punjab cities.

Shami, S. A.; Schmitt, Linc; Bittles, AH

doi:10.1136/jmg.26.4.267

Cited by 67 publications

(38 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The consanguinity rate was observed to be 56.72% in the study sample. This estimate is higher than previous estimates in the urban Pakistani populations of Jhelum, Gujrat, Rawalpindi, Sialkot, Sahiwal, Faisalabad, Lahore and Quetta (Shami et al, 1989;Yaqoob et al, 1993;Mian & Mushtaq, 1994). The observed consanguinity level in the Sargodha population is, however, less than the estimates reported for Gujranwala, Bhimber and Malakand districts, and the overall estimates for the Pakistani population (Shami et al, 1989;Jabeen & Malik, 2014;Sthanadar et al, 2014).…”

Section: Discussioncontrasting

confidence: 65%

“…This estimate is higher than previous estimates in the urban Pakistani populations of Jhelum, Gujrat, Rawalpindi, Sialkot, Sahiwal, Faisalabad, Lahore and Quetta (Shami et al, 1989;Yaqoob et al, 1993;Mian & Mushtaq, 1994). The observed consanguinity level in the Sargodha population is, however, less than the estimates reported for Gujranwala, Bhimber and Malakand districts, and the overall estimates for the Pakistani population (Shami et al, 1989;Jabeen & Malik, 2014;Sthanadar et al, 2014). This study nonetheless confirms that first cousin marriages remain the most common type of marital union, constituting 87% of consanguineous unions and 49% of total marriages, respectively (Shami et al, 1989;Hussain & Bittles, 1998).…”

Section: Discussioncontrasting

confidence: 65%

See 1 more Smart Citation

Pattern of Consanguinity and Inbreeding Coefficient in Sargodha District, Punjab, Pakistan

Hina

Malik

2014

J. Biosoc. Sci.

View full text Add to dashboard Cite

Consanguinity is widespread in Pakistan. The majority of studies on consanguinity in Pakistan have been carried out in urban metropolitan areas, and data on rural populations are scarce. The present cross-sectional study was conducted in Sargodha district, upper Punjab, Pakistan where the majority of the population reside in rural areas. A random sample of 1800 married females belonging to six tehsils of Sargodha district was obtained and differentials in consanguinity rates and inbreeding coefficient (F) were investigated. The consanguinity rate was calculated to be 56.72% and the inbreeding coefficient was 0.0348. First cousin unions had the highest representation (49.11% of all marriages), and marriages up to distantly related/Biradari constituted 67.94% of all marriages. Among the six tehsils, consanguinity rates ranged from 50.38% in Bhalwal to 62.88% in Sillanwali. A high rate of consanguinity was observed in subjects speaking the Punjabi language, those with self-arranged/arranged-love marriages and those engaged in professional jobs. With respect to the occupation of husbands the highest consanguinity rate was found among landowners (77.59%; F=0.0539) and businessmen (62.62%; F=0.0377). However, consanguinity did not appear to be associated with rural/urban origin or literacy level. The data showed a wide variation in consanguinity rate and inbreeding coefficient across socio-demographic strata in the Sargodha district population. A comparison of Sargodha with other populations of Punjab also showed regional heterogeneity in the pattern of consanguinity, warranting further studies.

show abstract

Section: Discussioncontrasting

confidence: 65%

Section: Discussioncontrasting

confidence: 65%

Pattern of Consanguinity and Inbreeding Coefficient in Sargodha District, Punjab, Pakistan

Hina

Malik

2014

J. Biosoc. Sci.

View full text Add to dashboard Cite

show abstract

“…Consanguineous marriages are generally associated with an increased incidence of genetic diseases [Schull, 1958;Naderi, 1979;Harper, 1984;Gatrad et al, 1984;Magnus et al, 1985], poor growth [Honeyman et al, 1987], and infant mortality [Fraser and Biddle, 1976;Magnus et al, 1985;Shami et al, 1989]. More specifically, we recently demonstrated a markedly high rate of consanguineous matings among Israeli Arab communities which was associated with a distinct increase in major malformations among offspring of first-cousin matings (15.8%) compared to unrelated matings (5.8%) [Jaber et al, 1992].…”

Section: Discussionmentioning

confidence: 96%

Consanguinity and common adult diseases in Israeli Arab communities

et al. 1997

View full text Add to dashboard Cite

Consanguinity has a deleterious effect with regard to congenital malformation and rare autosomal recessive diseases; however, little information exists on its role in multifactorial common adult morbidity. We investigated the effects of consanguinity on the prevalence of common diseases in adulthood, including diabetes mellitus, myocardial infarction, bronchial asthma, and duodenal ulcer. As part of a larger study investigating the inbreeding coefficient in the Israeli-Arab community, we distributed questionnaires to parents of 4,100 second-grade students in 158 randomly chosen schools. Among the 3,772 responders (92%), 34.8% of the students' fathers and 31% of their mothers were found to be born to consanguineous matings. There was no difference in the prevalence (males, females) between the offspring of consanguineous versus non-consanguineous matings for diabetes mellitus (consanguinity: 4.3%, 1.5% vs. non-consanguinity: 2.9%, 1.6%) myocardial infarction (2.7%, 0.03% vs. 2.3%, 0.03%), bronchial asthma (2.4%, 2.0% vs. 3.7%, 2.3%), or duodenal ulcer (7.0%, 3.0% vs. 7.8%, 2.9%), respectively. The study suggests that even in a population with a high rate of consanguinity, there is no significant increase in the prevalence of these common adult diseases.

show abstract

“…Nos résultats concordent avec ceux de plusieurs études menées dans les pays d'Asie, qui ont montré les effets de la consanguinité sur la mortalité infantile en Arabie Saoudite ( Wong, Anokute 1990), en Turquie (Guz et al 1989 ;Tuncbilek, Koc 1994), au Pakistan (Shami et al 1989 ;Grant, Bittles 1997 ;Hussain et al 2001) et en Inde ( Verma et al 1992 ;Banerjee, Roy 2002 Contrairement à ce qui précède, Al-Awadi et al, (1986) et d'autres auteurs ont conclu, à l'issue d'études sur la mortalité prénatale et postnatale au Sud de l'Inde et au Koweït, une indépendance entre la consanguinité et la mortalité (Yaqoob et al, 1998).…”

Section: Etude Sur La Base Du Coefficient De Consanguinitéunclassified

Etude De L’impact De La Consanguinité Sur La Santé Des Descendants Dans La Population De Tiflet (Maroc)

Zhour

Ahmed

Soulaymani

et al. 2016

ESJ

View full text Add to dashboard Cite

Several studies confirm the implication of the consanguinity in health problems and some countries still preserve this marital behavior. In this study, our objective is the analysis of consanguinity's impact on descendants' health in the Tiflet city and its regions (Northwest of Morocco). Data was collected between June and November 2012 and it was conducted on 1000 families. The calculation of the rate of the mortality concerned 3345 alive born descendants, while the biological effects of the consanguinity study was made on 3241 descendants. The results of this study show a significant association between the consanguinity and its incidence on health, such as the morbidity, the mortality and the abortion in the descendants.

show abstract

Consanguinity related prenatal and postnatal mortality of the populations of seven Pakistani Punjab cities.

Cited by 67 publications

References 18 publications

Pattern of Consanguinity and Inbreeding Coefficient in Sargodha District, Punjab, Pakistan

Pattern of Consanguinity and Inbreeding Coefficient in Sargodha District, Punjab, Pakistan

Consanguinity and common adult diseases in Israeli Arab communities

Etude De L’impact De La Consanguinité Sur La Santé Des Descendants Dans La Population De Tiflet (Maroc)

Contact Info

Product

Resources

About