Conscious sedation with midazolam intravenously for a patient with Parkinson’s disease and unpredictable chorea-like dyskinesia

Abstract

Oral surgery can be difficult in patients with chorea-like dyskinesia, which is common in those on long-term levodopa medication for Parkinson's disease, and we know of no conclusive evidence to indicate whether conscious sedation with midazolam is effective in such cases. We report a patient in whom levodopa-induced chorea-like dyskinesia disappeared when midazolam was given intravenously for conscious sedation.

Successful Management of Parkinson's Disease Dyskinesia During Local Anesthesia With Dexmedetomidine

“…Midazolam was more useful than propofol for alleviating LID during local anaesthesia and it stimulates the GABA receptors to regulate the thalamus and brainstem through the basal ganglia [7]. However, midazolam has a longer half-life and slightly poorer adjustability than propofol, so care should be taken with dosage.…”