Consensus Conference on Clinical Management of pediatric Atopic Dermatitis

Galli, Elena; Neri, Iria; Ricci, Giampaolo; Baldo, Ermanno; Barone, M.; Fortina, Anna Belloni; Bernardini, Roberto; Berti, Irene; Caffarelli, Carlo; Calamelli, Elisabetta; Capra, Lucetta; Carello, Rossella; Cipriani, Francesca; Comberiati, Pasquale; Diociaiuti, Andrea; Hachem, Maya El; Fontana, Elena; Gruber, Michaela; Haddock, Ellen S.; Maiello, Nunzia; Meglio, Paolo; Patrizi, Annalisa; Peroni, Diego; Scarponi, Dorella; Wielander, Ingrid; Eichenfield, Lawrence F.

doi:10.1186/s13052-016-0229-8

Cited by 69 publications

(86 citation statements)

References 257 publications

(289 reference statements)

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“…The Polish, Singaporean, and European guidelines are the only three that warn against certain compounds in moisturizers, such as urea, sodium chloride, and propylene glycol . Additionally, the Polish and Italian guidelines are the only ones that recommend specific ingredients such as petrolatum, ceramides, and glycerol . The European guidelines discuss the benefit of emollients “plus,” which contain active ingredients that do not qualify as a topical drug.…”

Section: Resultsmentioning

confidence: 99%

“…Because conventional soaps strip the skin's natural oil and alkalize stratum corneum (SC) pH, the use of nonsoap, nonirritant, hypoallergenic, and neutral pH cleansers is generally recommended. The U.S., Korean, and Italian guidelines specifically recommend the use of synthetic syndets as nonsoap alternatives . Differences also exist regarding bath additive recommendations.…”

Section: Resultsmentioning

confidence: 99%

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A comparison of international management guidelines for atopic dermatitis

LePoidevin

Lee

Shi

2018

Pediatric Dermatology

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Background/Objectives Atopic dermatitis (AD) is a chronic condition that is predominantly found in pediatric patients and commonly presents therapeutic challenges. The management of AD encompasses a variety of factors, and the pillars of optimal management revolve around skin barrier repair and antiinflammatory, antimicrobial, and antipruritic treatment. AD management guidelines exist in various geographic regions globally. The purpose of this review was to compare international guidelines to highlight the similarities and variances among populations and skin types. Comparisons were made for recommendations regarding moisturization, bathing, wet wrap therapy, topical corticosteroids, topical calcineurin inhibitors, antihistamines, antipruritics, antibiotics, systemic immunosuppressants, and biologics. Methods A literature search of the PubMed, EMBASE, and MEDLINE databases was performed for published guidelines in each geographic region. Inclusion criteria included publications available in English that were established by a dermatological association or group including dermatologists, pertained to the treatment of AD in humans, were the most recent guidelines available that were published between 2007 and 2018, and included comprehensive treatment recommendations. Results Publications from Europe, North America, Asia, the Asia‐Pacific region, Australia, and Africa were reviewed, encompassing 14 guidelines. Notable diversity exists across these guidelines regarding recommendations for moisturization and bathing, as well as topical and systemic therapies for AD. Conclusions Due to the heterogeneity of the disease and regional treatment accessibility, complete standardization of AD management guidelines may be difficult. Nevertheless, more consensus on management guidelines is needed, and recommendations should be updated as new treatment modalities become available.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

A comparison of international management guidelines for atopic dermatitis

LePoidevin

Lee

Shi

2018

Pediatric Dermatology

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“…Topical or systemic corticosteroids are still considered the mainstay therapy for the treatment of moderate-to-severe AD. They are normally used as anti-inflammatory medications to treat AD in any stage of inflammation and to reduce itching [14]. However, long-term use and the overdosage of corticosteroids may cause a series of adverse effects, including atrophy, hypopigmentation, striae distensae, and skin infections [15].…”

Section: Textiles-based Complementary Therapymentioning

confidence: 99%

“…A wet-wrap dressing is a double layer of tubular bandage or gauze consisting of a first moist inner layer and second dry outer layer and involves the application of a topical medication (Figure 1) [14,19]. The use of dampened bandages to reduce pruritus and inflammation is an ancient medical remedy.…”

Section: Wet-wrap Dressingmentioning

confidence: 99%

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Functionalized Textile Based Therapy for the Treatment of Atopic Dermatitis

2017

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Atopic dermatitis (AD) is a common chronic inflammatory skin condition characterized by intense puritus and skin dryness. The pathogenesis for AD has not been fully understood to date. Complementary therapies are very popular as effective treatment for AD among clinical practitioners. This study presents a comprehensive review of published works associated with textiles-based complementary therapies for AD treatment such as wet-wrap dressing, functionalized textiles, and the application of hydrogel techniques in the textile industry to provide a better understanding of the development and design of new textiles-based transdermal therapies.

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General practitioners' explanation and advice on childhood eczema and factors influencing their treatment strategy: A qualitative study

Halewijn

Warendorff

Bohnen

et al. 2022

Skin Health and Disease

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Background Atopic dermatitis (AD) is common in children and the majority of children can be treated by the general practitioner (GP). Various factors can influence the GP's treatment strategy and may lead to less effective treatment. The objective is to gain insight into the treatment goal, treatment strategy, explanation and advice given by GPs when dealing with AD in children and to explore which factors play a role in the choice of pharmacological treatment. Methods Semi‐structured interviews in primary care in the Netherlands were audio‐recorded and transcribed. All data were analysed according to the six‐steps approach of inductive thematic analysis. Results We interviewed 16 GPs. Treatment goals mainly focussed on the short term. GPs discussed the importance of emollient use and emphasised emollients as the basis of treatment. We found that several factors played a role in prescribing topical corticosteroids (TCS); severity of the AD, age of the child, skin type, corticophobia among parents and GPs, experience of side effects and dermatological experience. GPs reported giving limited advice about the use of TCS and prescribed medication that is not recommended by the guideline. Conclusion Various factors seem to influence GPs' treatment strategy for AD in children. More attention and education about the use and safety of TCS in children during GP training, continuous medical education, probably improve treatment in line with guidelines and can lead to more confidence and knowledge about TCS among GPs, which ultimately may improve the education and self‐management of patients.

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Consensus Conference on Clinical Management of pediatric Atopic Dermatitis

Cited by 69 publications

References 257 publications

A comparison of international management guidelines for atopic dermatitis

A comparison of international management guidelines for atopic dermatitis

Functionalized Textile Based Therapy for the Treatment of Atopic Dermatitis

General practitioners' explanation and advice on childhood eczema and factors influencing their treatment strategy: A qualitative study

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