Consensus en endoscopie digestive : prise en charge des œsophagites caustiques

Lachaux, A.; Mas, Emmanuel; Breton, A; Barange, Karl; Héresbach, D.; Molard, B Richard

doi:10.1007/s10190-011-0191-7

Cited by 23 publications

(15 citation statements)

References 41 publications

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“…Beyond 24 hours, endoscopy exposes to a greater risk of perforation in case of severe lesions. Although there are few precise data on this point, it can be considered that endoscopy is not recommended beyond 24 hours after exposure to caustic, and in this case should be very cautious and if possible under sedation [13].…”

Section: Discussionmentioning

confidence: 99%

Caustic Digestive Lesions in Adults: Epidemiological, Endoscopic and Therapeutic Aspects at Idrissa Pouye General Hospital (Dakar, Senegal)

Guèye¹

2020

ARGH

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Introduction: Ingestion of caustic products is a diagnostic and therapeutic emergency. Its severity is related to the risk of death and digestive functional sequelae. Common in children, following accidental ingestion, many studies have been devoted to it in the pediatric environment. However, data on adult populations are rare in our context. The aim of this work was to describe the profile of patients hospitalized for caustic ingestion, the context of occurrence, the endoscopic lesions observed, their evolution and their therapeutic modalities. Patients and methods:This was a descriptive retrospective study in the Hepato-Gastroenterology Department of the Idrissa Pouye General Hospital (HOGIP) over a period of 8 years (March 2008-March 2016. The records of patients over 15 years old, hospitalized for caustic ingestion were collected. The age, sex, circumstances of occurrence, nature of the caustic, consultation and endoscopy time, endoscopic lesions and their therapeutic modalities were studied. Results:Of the 2750 patients hospitalized during the study period, 25 were admitted for ingestion of digestive caustic products, corresponding to a prevalence of 0.9%. Three records were not searched. The following data were obtained from the analysis of 22 records. The mean age was 36.5 years (range: 16-82 years) with a sex ratio of 0.7 (13 females). Ingestion of the caustic was voluntary in 16 cases (11 women). The main motivations for the women were family conflicts. A regular intake of hallucinogenic substances (Indian hemp) was noted in 80% of men who voluntarily ingested a caustic product. Caustic soda was the product most often incriminated. The average quantities of caustic ingested were respectively 100cc and 300cc depending on whether the ingestion was accidental or voluntary. The median consultation time was 5 hours (30min-28d) and the median endoscopy time was 48 hours (16h-70d). The main acute esophageal lesions objectified were grade IIB (46.8%) and IIIA (37.3%) according to Di Costanzo's classification. At the gastric level, grade I and IIa lesions were present in 36.4% and 43% of cases respectively. Control endoscopy revealed esophageal or gastric stenosis in 8 cases (36.4%) and 2 cases (9%) respectively. Therapeutically, a total diet was instituted in all patients. The average duration of the diet was 15 days (2 days -21 days). Parenteral nutrition was introduced in 5 patients (22.7%). PPI therapy and rehydration were the standard treatment in all patients. Eight patients received endoscopic esophageal dilations. The mean number of dilation sessions was 4 (range: 2-11). Gastroentero anastomosis was performed in 2 patients. One case of death was recorded at D7 of hospitalization following septic shock in a patient with grade IIIB esogastric lesions of Di Costenzo. Conclusion:The ingestion of caustic products in the hospitalization unit of the Hepato-Gastroenterology Department of Idrissa Pouye General Hospital is more frequent in women, most often related to an attempt at autolysis in the context of fami...

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Section: Discussionmentioning

confidence: 99%

Caustic Digestive Lesions in Adults: Epidemiological, Endoscopic and Therapeutic Aspects at Idrissa Pouye General Hospital (Dakar, Senegal)

Guèye¹

2020

ARGH

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“…Quoting data compiled by the World Health Organization, Lachaux et al (2011) described that the worldwide estimated incidence of corrosive ingestions is 110/100,000 persons annually. Incidences in various regions were the following: United States, 19/100,000 population; Eastern Mediterranean area, 187/100,000 population; Asia, 243/100,000 population.…”

Section: Other Scope Of the Problem Datamentioning

confidence: 99%

“…Worldwide corrosive ingestion mortality was 310,000 persons in 2004, or 4.8/100,000 population per year. Children accounted for approximately 30% of corrosive ingestion cases (Lachaux et al 2011).…”

Section: Other Scope Of the Problem Datamentioning

confidence: 99%

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Corrosive substances ingestion: a review

Hall

Jacquemin²,

Henny³

et al. 2019

Critical Reviews in Toxicology

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Corrosive chemical substance ingestions are a major problem, especially in developing countries, but also in developed countries such as the United States, France, and Belgium. Ingestions may be deliberate as suicide attempts (mostly in adolescents and adults) or accidental (mostly in children). The results can be devastating in terms of individual suffering and disability, but also in terms of resource utilization and costs. In developing countries, outcomes may be worse because of limited medical/surgical resources. Common sequelae include gastrointestinal (GI) tract (esophagus, stomach, pylorus, and duodenum) stricture formation, GI tract perforation, and hemorrhage. Systemic effects may also occur, such as disseminated intravascular coagulation (DIC), multi-organ system failure, and sepsis. Various interventions in the acute phase to reduce the severity of injury have been attempted, but there are no large controlled clinical trials to demonstrate efficacy. Dilation therapy in various forms is commonly used for the treatment of strictures and a variety of surgical procedures including esophagectomy and delayed replacement may be required in severe corrosive injury cases.

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“…The global incidence, according to WHO in 2004, was 110 cases per 1000 people per year, of which 30% were children [2] [4] [5]. In developed countries, the incidence has decreased considerably due to the impact of prevention measures in the populations [6] [7] [8]. In developing countries, particularly in sub-Saharan Africa, prevalence is increasing.…”

Section: Introductionmentioning

confidence: 99%

Ingestion of Caustics by Children in Brazzaville (CONGO)

Ollandzobo¹,

Ahoui-Apendi²,

Mimiesse-Monamou³

et al. 2018

OJPed

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Ingestion of caustics by children is serious because of the increase in their frequency and the difficulties due to their management. Objective: To improve the management of caustic lesions in Pediatric Department at the University Hospital of Brazzaville. Patients and Methods: Prospective study was conducted from January 2014 to December 2015 in the Pediatric Departments of the UHB and centers of digestive endoscopy in Brazzaville. All children who ingested a caustic product and hospitalized were included after obtaining parental's consent. The studied parameters were: Age, sex, nature and quantity of the caustic, the family's attitude, clinical signs, endoscopic results according to Zagar's classification, therapeutic modalities and evolution. Results: 8292 children were hospitalized and 68 because of the ingestion of caustic, a frequency of 0.8%. The average age was 23.6 months [2 months-16 years]. The male sex was predominant (57.4%). Ingestion was accidental in 88.2% and voluntary in 11.8%. Factors favoring ingestion were storage methods (81.5%) and parental's inattention or negligence (10.8%). Bleach was the most incriminated caustic (54.4%) followed by caustic soda (29.4%). The estimated quantity ingested was assumed to be minimal in 61.7%. Unsuitable acts were practiced by the family before the medical consultation in 66.1%. The dominant symptoms were digestive (47%) and neurological (25%). The average time to perform endoscopy was 48 hours in 88.2%. Endoscopy revealed lesions in 51.7%, the different stages were I (12 cases), II (16 cases) and III (3 cases). The mains factors of gravity were inappropriate gestures (85%) and the non-respect of the fasting (9%). Proton pump inhibitors were used in 50%. The evolution was favorable for in 73.5%. Conclusion: Ingestion of caustics by children is most often accidental favored by the inadequate pack

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Consensus en endoscopie digestive : prise en charge des œsophagites caustiques

Cited by 23 publications

References 41 publications

Caustic Digestive Lesions in Adults: Epidemiological, Endoscopic and Therapeutic Aspects at Idrissa Pouye General Hospital (Dakar, Senegal)

Caustic Digestive Lesions in Adults: Epidemiological, Endoscopic and Therapeutic Aspects at Idrissa Pouye General Hospital (Dakar, Senegal)

Corrosive substances ingestion: a review

Ingestion of Caustics by Children in Brazzaville (CONGO)

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