Consensus statement on management in the UK: Transoral laser assisted microsurgical resection of early glottic cancer

Bradley, Patrick J.; MacKenzie, Kenneth; Wight, Richard G.; Pracy, Paul; Paleri, Vinidh

doi:10.1111/j.1749-4486.2009.01944.x

Cited by 39 publications

(43 citation statements)

References 26 publications

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“…27 Historically, most early stage laryngeal tumours were treated with radiotherapy, although there is an increasing trend in the use of endoscopic resection techniques. 28 For advanced disease, radical surgery with adjuvant radiotherapy or concomitant chemo-radiation is the curative treatment of choice. 29 It is however, unclear why women diagnosed with glottal tumours have poorer survival than men with tumours at the same anatomical location, and in contrast, why men diagnosed with supraglottal cancers have lower survival than women with supraglottal tumours.…”

Section: Discussionmentioning

confidence: 99%

Trends and inequalities in laryngeal cancer survival in men and women: England and Wales 1991–2006

Ellis¹,

Rachet²,

Birchall³

et al. 2012

Oral Oncology

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Objectives Laryngeal cancer in men is a relatively common malignancy, with a marked socioeconomic gradient in survival between affluent and deprived patients. Cancer of the larynx in women is rare. Survival tends to lower than for men, and little is known about the association between deprivation and survival in women with laryngeal cancer. This paper explores the trends and socio-economic inequalities in laryngeal cancer survival in women, with comparison to men. Materials and MethodsWe examined relative survival among men and women diagnosed with laryngeal cancer in England and Wales during 1991-2006, followed up to 31 December 2007. We estimated the difference in survival between the most deprived and most affluent groups (the 'deprivation gap') at 1 and 5 years after diagnosis, for each sex, anatomical subsite and calendar period. ResultsFive year survival for all laryngeal cancers combined was up to 8% lower in women than in men. This difference is only partially explained by the differential distribution of anatomical subsites in men and women. Disparities in survival between men and women were also present within specific subsites. In contrast to men, there was little evidence of a consistent deprivation gap in survival for women at any of the anatomical subsites. ConclusionThe stark socioeconomic inequalities in laryngeal cancer survival in men do not appear to be replicated in women. The origins of the socio-economic inequalities in survival among men, and the disparities in survival between men and women at specific tumour subsites remains unclear.246 words

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Section: Discussionmentioning

confidence: 99%

Trends and inequalities in laryngeal cancer survival in men and women: England and Wales 1991–2006

Ellis¹,

Rachet²,

Birchall³

et al. 2012

Oral Oncology

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“…29 A mixture of follow-up regimens was noted, and the ENT-UK Head & Neck consensus statement suggested a voice assessment prior to, within 3 months and at 12 months following surgery, preferably with stroboscopy. 30 No study was randomised so apparent positive findings may reflect allocation bias; the patients in Goor 23 and Peeters 25 were allocated to TLM if laryngostroboscopy demonstrated a superficial tumour and to RT if a deeper more infiltrating tumour was diagnosed. Thus, the 'better' vocal outcome may be attributed to case selection.…”

Section: Discussionmentioning

confidence: 99%

“…The ENT-UK Head & Neck consensus statement suggested that patients should be given the choice of TLM but with caution of the adverse voice outcomes when the AC is treated surgically. 30 It is of interest that this latter statement has been made, despite a lack of high quality research to support it.…”

Section: Anterior Commissurementioning

confidence: 99%

Quality of life and functional outcomes in the management of early glottic carcinoma: a systematic review of studies comparing radiotherapy and transoral laser microsurgery

Spielmann

Majumdar

Morton

2010

Clinical Otolaryngology

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Background: Early glottic carcinoma can be managed by radiotherapy and transoral laser microsurgery with similar control and survival rates. The functional and quality of life outcomes of these interventions are therefore important to guide management. Objective of review: To compare the different treatment modalities for early glottic carcinoma with respect to quality of life, post-treatment voice character and swallowing outcomes. Type of review: A systematic review of the literature with defined search strategy. Search strategy: Searches of EBM databases, and literature databases using key words: glotti*, laryn*, neoplasm, radiotherapy and laser surgery from 1970 to November 2009. Articles were screened for relevance using predetermined inclusion and exclusion criteria. Evaluation method: Articles reviewed by authors and data compiled in tables for analysis. Results: No randomised controlled trials were identified. There were 15 studies reporting vocal outcomes, and

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“…In 2009, the ENT UK Head and Neck Group released a consensus statement on transoral laser microsurgery for early glottic cancer which provides guidance on the standards for patient selection, surgical care and follow up. 3 The Head and Neck Unit at NHS Lothian, Edinburgh, UK, has offered transoral laser microsurgery for early laryngeal cancer since 2002. This study aimed to analyse our practice of transoral laser microsurgery compared with standards outlined by the consensus statement of the ENT UK Head and Neck Group and to present the oncological outcomes for local and distant tumour control.…”

Section: Introductionmentioning

confidence: 99%

Audit of transoral laser-assisted microsurgical resection of early laryngeal cancer

Amir

Vernham

2015

J. Laryngol. Otol.

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Consensus statement on management in the UK: Transoral laser assisted microsurgical resection of early glottic cancer

Cited by 39 publications

References 26 publications

Trends and inequalities in laryngeal cancer survival in men and women: England and Wales 1991–2006

Trends and inequalities in laryngeal cancer survival in men and women: England and Wales 1991–2006

Quality of life and functional outcomes in the management of early glottic carcinoma: a systematic review of studies comparing radiotherapy and transoral laser microsurgery

Audit of transoral laser-assisted microsurgical resection of early laryngeal cancer

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