BackgroundMedication errors are preventable events that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the healthcare professional or patient. Medication errors in hospitalised adults may cause harm, additional costs, and even death.
ObjectivesTo determine the e ectiveness of interventions to reduce medication errors in adults in hospital settings.
Search methodsWe searched CENTRAL, MEDLINE, Embase, five other databases and two trials registers on 16 January 2020.
Selection criteriaWe included randomised controlled trials (RCTs) and interrupted time series (ITS) studies investigating interventions aimed at reducing medication errors in hospitalised adults, compared with usual care or other interventions. Outcome measures included adverse drug events (ADEs), potential ADEs, preventable ADEs, medication errors, mortality, morbidity, length of stay, quality of life and identified/ solved discrepancies. We included any hospital setting, such as inpatient care units, outpatient care settings, and accident and emergency departments.
Data collection and analysisWe followed the standard methodological procedures expected by Cochrane and the E ective Practice and Organisation of Care (EPOC) Group. Where necessary, we extracted and reanalysed ITS study data using piecewise linear regression, corrected for autocorrelation and seasonality, where possible.