Cyprinella panarcys is considered to be endemic to the upper Río Conchos drainage of Mexico. A single individual of C. panarcys was collected from the Rio Grande along the USA–Mexico international border (Presidio Co., Texas) in April 2018. This is the first record of C. panarcys from outside of the Río Conchos and the first record from the USA. A brief description of the external morphology of the individual collected is provided along with an updated distribution map for the species.