Conservative treatment for breast cancer: long-term results (15 years)

Blood Hemoglobin Level and Treatment Outcome of Early Breast Cancer

“…Though retrospective studies, particularly on small samples, may be misleading, demographic data, treatment techniques and outcome of our BCS-RT and MRM patients compare well to literature data [9,17,28,29,31,39,41] and seem to exclude an eventual selection bias. Further, by meticulously forming both patient cohorts preceding the statistical analyses we made sure to fulfill one of the major requirements for prognostic factor studies [34].…”

Is Regional Lymph Node Irradiation Necessary in Stage II to III Breast Cancer Patients With Negative Pathologic Node Status After Neoadjuvant Chemotherapy?

“…Although recent technical advances have reduced the risk of postradiotherapy complications, irradiation should still be reserved for patient subgroups in whom it has been shown to be consistently beneficial. Supraclavicular lymph node irradiation has been linked to an increased risk of arm edema (28)(29)(30), brachial plexopathy (31)(32)(33), pneumonitis (34)(35)(36), and esthetic sequelae (37)(38)(39). Meric et al, in a series of 294 prospectively monitored patients, found that approximately 1 in 10 patients developed Grade $2 complications such as arm edema, breast skin fibrosis, and limited arm motion (39).…”

Long‐term results of neoadjuvant radiation therapy for breast cancer

“…Radiation therapy has been clearly demonstrated to reduce both local and regional recurrence and its use with breast-conserving surgery has been established worldwide as an important means of improving quality of life [10]. In 1970, Pierquin and co-workers [11,12], among others, developed a technique for treatment of "operable" breast cancer patients by breast conservation and radiation therapy. The present authors have developed the concept of treating T2 and T3 tumors conservatively (as is currently done for T1 and small T2 tumors), in an attempt to improve local control and produce acceptable cosmetic results [13][14][15].…”