Conservative Treatment of Neonatal Primary Megaureter

Renal Function and Urine Drainage after Conservative or Operative Treatment of Primary (Obstructive) Megaureter in Infants and Children

“…A spontaneous improvement rate of 43% to 100 % (median 90) of the unoperated patients was registered. In studies which refer exclusively to asymptomatic pre-and/ or directly post-natally diagnosed megaureters, the rate of the children operated on is only between 0 and 28% [3,8,[19][20][21]. A long-time follow-up revealed that the performance of the kidneys with a primary megaureter produced the expected growth during the organ maturation in case of conservative treatment [5].…”

Complications and long-term outcome of primary obstructive megaureter in childhood

“…With modern ultrasound techniques, about 40% of POMs are discovered prenatally [6] and the fraction of symptomatic children decreased to 22-50% [7,8]. In the 1990s, several reports documented the high rate of spontaneous regression of prenatally diagnosed POM [7,[9][10][11][12][13]. Even though chronic renal failure has been described in rare cases of adults with bilateral POM [14], the lack of functional impairment of the great majority of kidneys with POM is an additional argument for taking a conservative approach [15].…”

Management of Primary Obstructive Mega Ureter, By Kalicinski Folding Technique: A Tertiary Care Center Experience

“…Diagnostic criteria include: dilated ureter, absence of vesicoureteral reflux, absence of infravesical obstruction and absence of distal ureteral obstruction. During the past 10 years there has been an increasing trend towards conservative management, the role of extended follow-up into early adulthood also has been advocated based on worsening of some previously stable megaureters at or beyond puberty 7,8,9,10 . In this approach three main variables need to be monitored, i.e.…”

“…Symptoms are relatively straightforward to follow and surgery is indicated if there is persistent pain, breakthrough pyelonephritis or calculi 9,10 . …”