Conservative treatment of phimosis with fluticasone proprionate 0.05%: A clinical study in 1185 boys

Zavras, Nick; Christianakis, Efstratios; Mpourikas, D.; Ereikat, K.

doi:10.1016/j.jpurol.2008.11.006

Cited by 22 publications

(13 citation statements)

References 21 publications

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“…During recent years, several articles on the use of topical steroids for the treatment of phimosis have reported similar success rates ranging from 70% to 90% [1,2,10-15]. The success rate in our study was 68.2 %, which is relatively low compared with other studies.…”

Section: Discussioncontrasting

confidence: 43%

“…The reported topical steroid agents, regimens, and the success rate of treatment have varied [1,2,10-15]. Moreover, the potency of the topical steroids used ranges from class I to class VII.…”

Section: Discussionmentioning

confidence: 99%

“…Although the most suitable application period of topical steroid ointment is still debatable, most studies regarding the use of topical steroids in phimosis suggest that application of a topical steroid for 4 weeks is safe and reliable [1,2,10-15]. For this reason, the parents of the boy were instructed to apply 0.05% clobetasol propionate cream to the slightly retracted foreskin and to massage gently while retracting the foreskin 20 times twice a day, after washing or bathing, for 4 consecutive weeks.…”

Section: Methodsmentioning

confidence: 99%

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Effect of Topical Steroid (0.05% Clobetasol Propionate) Treatment in Children With Severe Phimosis

Lee

2013

Korean J Urol

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PurposeWe report our experience with the use of a topical steroid, 0.05% clobetasol propionate, for the treatment of phimosis with clinical complications.Materials and MethodsThis was a retrospective analysis of the clinical outcomes of all patients presenting with phimosis to a single institution during the time period from October 2008 to May 2012. A total of 88 patients who had a Kikiros retractability grade of 4 or 5 and phimosis-associated clinical complications, such as ballooning of the prepuce, balanoposthitis, or a history of urinary tract infection (UTI), were instructed to apply 0.05% clobetasol propionate cream to the slightly retracted foreskin and to massage gently while retracting the foreskin. The efficacy of treatment was evaluated at 4 weeks from the initiation of therapy.ResultsA total of 60 of the 88 patients (68.2%) showed a complete response (i.e., full retraction of the foreskin) to the therapy. The phimotic ring disappeared in 25 of the 88 patients (28.4%) after treatment. Patients who had a history of balanoposthitis, smegma, ballooning of the prepuce, or UTI showed significantly poorer improvement in preputial retraction (p<0.001, p<0.001, p<0.001, and p=0.02, respectively) and phimotic ring disappearance (p<0.001, p=0.001, p<0.001, and p=0.001, respectively) after treatment. No significant local or systemic side effects were associated with the administration of topical steroids.ConclusionsTopical application of 0.05% clobetasol propionate cream and skin stretching is a safe, simple, and effective procedure with no significant side effects for severe phimosis in prepubertal boys.

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Section: Discussioncontrasting

confidence: 43%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Effect of Topical Steroid (0.05% Clobetasol Propionate) Treatment in Children With Severe Phimosis

Lee

2013

Korean J Urol

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“…Once retracted, it should be dried to prevent distal preputial irritation by urine, and the cream or ointment should be applied. The recurrence rate of phimosis after the cessation of topical steroids has been noted in the literature to be between 3 and 11% . The recurrence of phimosis is believed to be associated with poor hygiene and the discontinuation of daily foreskin retraction …”

Section: Phimosismentioning

confidence: 99%

“…The recurrence rate of phimosis after the cessation of topical steroids has been noted in the literature to be between 3 and 11%. [31][32][33] The recurrence of phimosis is believed to be associated with poor hygiene and the discontinuation of daily foreskin retraction. 32,34…”

Section: Phimosismentioning

confidence: 99%

Circumcision in the paediatric patient: A review of indications, technique and complications

Prabhakaran

Ljuhar

Coleman

et al. 2018

J Paediatrics Child Health

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Circumcision is one of the most commonly performed surgical procedures in the world. Despite this, the practice of paediatric circumcision remains highly controversial, and continues to generate ongoing debate. This debate has become more relevant recently with the provisional guidelines from the Centers for Disease Control and Prevention recommending a change of practice. In this review article, we provide an overview of the history and incidence of circumcision, normal preputial development, types of phimosis, the absolute and relative indications for circumcision as well as the evidence base for its use as a preventative measure. Our aim is to provide paediatricians with a greater understanding of this common surgical procedure and the conditions it treats, to guide their clinical practice and parent counselling.

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Circumcision: Case Against Surgery Without Medical Indication

Schröder

2012

Surgical Guide to Circumcision

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Conservative treatment of phimosis with fluticasone proprionate 0.05%: A clinical study in 1185 boys

Cited by 22 publications

References 21 publications

Effect of Topical Steroid (0.05% Clobetasol Propionate) Treatment in Children With Severe Phimosis

Effect of Topical Steroid (0.05% Clobetasol Propionate) Treatment in Children With Severe Phimosis

Circumcision in the paediatric patient: A review of indications, technique and complications

Circumcision: Case Against Surgery Without Medical Indication

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