Conservative versus surgical treatment of venous leg ulcers: A prospective, randomized, multicenter trial

Gent, W.B. van; Hop, Wim C. J.; Praag, Marinus C. van; Mackaay, A. J. C.; Boer, E. M. de; Wittens, C.H.A.

doi:10.1016/j.jvs.2006.04.053

Cited by 165 publications

(121 citation statements)

References 12 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…Since its first description by Hauer in the 1980s, 1) SEPS has been accepted as an improved treatment modality in the surgical treatment of perforating vein insufficiency, particularly in cases with advanced skin changes. SEPS is performed in some facilities in North America [2][3][4][5] and Europe [6][7][8][9][10] as a component of the comprehensive treatment program for venous insufficiency. These previous studies presented favorable results with SEPS.…”

Section: Introductionmentioning

confidence: 99%

Subfascial Endoscopic Perforator Surgery Using Screw-Type Ports Is a Very Useful Component of a Comprehensive Treatment Program for Chronic Venous Insufficiency

Kusagawa¹,

Shomura²,

Komada³

et al. 2012

Annals of Vascular Diseases

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Subfascial Endoscopic Perforator Surgery Using Screw-Type Ports Is a Very Useful Component of a Comprehensive Treatment Program for Chronic Venous Insufficiency

Kusagawa¹,

Shomura²,

Komada³

et al. 2012

Annals of Vascular Diseases

View full text Add to dashboard Cite

show abstract

“…The data for RRs were based on a systematic review of RCTs7, which are usually considered to be the most valid form of evidence. At the time of publication of the systematic review7, the ESCHAR RCT21 reported substantially fewer recurrences after surgery at 4 years, whereas van Gent and co‐workers31 showed no difference in recurrence at 2 years. However, recently published long‐term follow‐up from the latter study showed that surgery almost halved the probability of recurrence at 10 years32, corroborating the outcome of the ESCHAR trial21.…”

Section: Discussionmentioning

confidence: 99%

Cost‐effectiveness of treatments for superficial venous reflux in patients with chronic venous ulceration

et al. 2018

View full text Add to dashboard Cite

BackgroundVenous leg ulcers impair quality of life significantly, with substantial costs to health services. The aim of this study was to estimate the cost‐effectiveness of interventional procedures alongside compression therapy versus compression therapy alone for the treatment of chronic venous leg ulceration.MethodsA Markov decision analytical model was developed. The main outcome measures were quality‐adjusted life‐years (QALYs) and lifetime costs per patient, from the perspective of the UK National Health Service at 2015 prices. Resource use included the initial procedures, compression therapy, primary care and outpatient consultations. The interventional procedures included superficial venous surgery, endothermal ablation and ultrasound‐guided foam sclerotherapy (UGFS). The study population was patients with a chronic venous ulcer who were eligible for either compression therapy or an interventional procedure. Data were obtained from systematic review and meta‐analysis of RCTs.ResultsSurgery gained 0·112 (95 per cent c.i. −0·011 to 0·213) QALYs compared with compression therapy alone, with a difference in lifetime costs of €−1330 (−3570 to 1262). Given the expected savings in community care, the procedure would pay for itself within 4 years. There was insufficient evidence regarding endothermal ablation and UGFS to draw conclusions.DiscussionThis modelling study found surgery to be more effective and less costly than compression therapy alone. Further RCT evidence is required for both endothermal ablation and UGFS.

show abstract

“…In a multivariate Cox regression analysis previous vein surgery was the only factor significantly associated with recurrent ulceration (p=.004) 26 . SEPS combined with superficial venous surgery leads to healing with a low recurrence rate in patients with open and healed venous ulcers [24][25][26][27][28] Rejection of clip(after one month) through port site sinus 2 % …”

Section: Discussionmentioning

confidence: 99%

Endoscopic Treatment of Chronic Venous Insufficiency by Interrupting Below Knee Perforating Veins: A Prospective Study

Kushwaha¹

2016

jmscr

View full text Add to dashboard Cite

Conservative versus surgical treatment of venous leg ulcers: A prospective, randomized, multicenter trial

Abstract: In conclusion, we suggest that patients with medial and/or recurrent ulceration should receive surgery combined with ambulatory compression therapy. A dedicated center should provide care for those patients.

Cited by 165 publications

References 12 publications

Subfascial Endoscopic Perforator Surgery Using Screw-Type Ports Is a Very Useful Component of a Comprehensive Treatment Program for Chronic Venous Insufficiency

Subfascial Endoscopic Perforator Surgery Using Screw-Type Ports Is a Very Useful Component of a Comprehensive Treatment Program for Chronic Venous Insufficiency

Cost‐effectiveness of treatments for superficial venous reflux in patients with chronic venous ulceration

Endoscopic Treatment of Chronic Venous Insufficiency by Interrupting Below Knee Perforating Veins: A Prospective Study

Contact Info

Product

Resources

About