Conserved and Divergent Features of Reproductive Neuroendocrinology in Teleost Fishes

Kah, Olivier; Dufour, Sylvie

doi:10.1016/b978-0-12-374932-1.00002-0

Cited by 12 publications

(15 citation statements)

References 211 publications

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“…5), although the latter is too faint to distinguish from background staining with certainty. We expected expression to be localized to the pars distalis, as it is the region of the teleost pituitary that produces the gonadotropins [35]. TSH 1 mRNA expression appeared to increase after exposure to a single long day (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…In stickleback, the pars distalis has extensive innervation from GnRH neurons [4]. As the pars distalis is the site of gonadotropin production and secretion in the vertebrate pituitary [35], this innervation supports the concept of a direct control of gonadotropins by GnRH.…”

Section: Discussionmentioning

confidence: 98%

“…In mammals and birds, the first short night elicits a similar response of TSHβ [22, 40, 46] but in the pars tuberalis of the pituitary [46, 63]. As the pars tuberalis as a distinct region of the pituitary is found only in tetrapods [35], the pulse of TSHβ1 in the stickleblack pars distalis indicates that function of the tetrapod pars tuberalis is likely contained within the pars distalis of teleosts.…”

Section: Discussionmentioning

confidence: 99%

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Conservation of the photoperiodic neuroendocrine axis among vertebrates: Evidence from the teleost fish, Gasterosteus aculeatus

O’Brien

Bourdo

Bradshaw

et al. 2012

General and Comparative Endocrinology

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Photoperiod, or length of day, has a predictable annual cycle, making it an important cue for the timing of seasonal behavior and development in many organisms. Photoperiod is widely used among temperate and polar animals to regulate the timing of sexual maturation. The proper sensing and interpretation of photoperiod can be tightly tied to an organism’s overall fitness. In photoperiodic mammals and birds the thyroid hormone pathway initiates sexual maturation, but the degree to which this pathway is conserved across other vertebrates is not well known. We use the threespine stickleback Gasterosteus aculeatus, as a representative teleost to quantify the photoperiodic response of key genes in the thyroid hormone pathway under controlled laboratory conditions. We find that the photoperiodic responses of the hormones are largely consistent amongst multiple populations, although differences suggest physiological adaptation to various climates. We conclude that the thyroid hormone pathway initiates sexual maturation in response to photoperiod in G. aculeatus, and our results show that more components of this pathway are conserved among mammals, birds, and teleost fish than was previously known. However, additional endocrinology, cell biology and molecular research will be required to define precisely which aspects of the pathway are conserved across vertebrates.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

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Conservation of the photoperiodic neuroendocrine axis among vertebrates: Evidence from the teleost fish, Gasterosteus aculeatus

O’Brien

Bourdo

Bradshaw

et al. 2012

General and Comparative Endocrinology

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“…In particular, the central regulation of reproduction in teleosts involves gonadotropin-releasing hormone (GnRH) neurons that stimulate the synthesis and release of gonadotrophins (Kah 2009;Kah and Dufour 2010;Zohar et al 2010), which also in all vertebrates stimulate gametogenesis and steroidogenesis (Schulz et al 2010;Lubzens et al 2010;Levavi-Sivan et al 2010). Activities of GnRH neurons and/or gonadotrops are directly or indirectly modulated by a plethora of neurohormones and or neurotransmitters, among which one finds dopamine Chang et al 1984;Kah et al 1987), serotonin (Khan and Thomas 1992;Somoza et al 1988), GABA (Trudeau et al 2000;Kah et al 1992), neuropeptide Y (Kah et al 1989), endorphins (Rosenblum and Peter 1989), and kisspeptins (Kanda et al 2008;Kitahashi et al 2009).…”

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confidence: 99%

Neuroendocrine Effects of Endocrine Disruptors in Teleost Fish

Page

Vosges

Servili

et al. 2011

Journal of Toxicology and Environmental Health, Part B

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Because a large proportion of potential endocrine disruptors (EDC) end up in surface waters, aquatic species are particularly vulnerable to their potential adverse effects. Recent studies identified a number of brain targets for EDC commonly present in environmentally relevant concentrations in surface waters. Among those neuronal systems disrupted by EDC are the gonadotropin-releasing hormone (GnRH) neurons, the dopaminergic and serotoninergic circuits, and more recently the Kiss/GPR54 system, which regulates gonadotropin release. However, one of the most striking effects of EDC, notably estrogen mimics, is their impact on the cyp19a1b gene that encodes the brain aromatase isoform in fish. Moreover, this is the only example in which the molecular basis of endocrine disruption is fully understood. The aims of this review were to (1) synthesize the most recent discoveries concerning the EDC effects upon neuroendocrine systems of fish and (2) provide, when possible, the underlying molecular basis of disruption for each system concerned. The potential adverse effects of EDC on neurogenesis, puberty, and brain sexualization are also described. It is important to point out the future environmental, social, and economical issues arising from endocrine disruption studies in the context of risk assessment.

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“…GABA plays an important role in the regulation of GnRH and gonadotropin (GTH) release in vertebrates Sloley et al 1992;Trudeau et al 1993aTrudeau et al , b, c, 2000. Furthermore, direct innervation of the neurohypophysis and adenohypophysis by GABA neurons has been demonstrated in goldfish Carassius auratus (Kah et al 1987;Kah and Dufour 2010). In teleost fishes, GABA-containing cell bodies were found in the preoptic area and tuberal regions of the hypothalamus (Martinoli et al 1990), and studies suggest that GABA is important in the early development of the teleost central nervous system (Ekstrom and Ohlin 1995;Doldan et al 1999).…”

Section: Distribution Of Gaba Neurotransmittermentioning

confidence: 99%

Lampreys: Biology, Conservation and Control

Docker¹

2015

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Conserved and Divergent Features of Reproductive Neuroendocrinology in Teleost Fishes

Cited by 12 publications

References 211 publications

Conservation of the photoperiodic neuroendocrine axis among vertebrates: Evidence from the teleost fish, Gasterosteus aculeatus

Conservation of the photoperiodic neuroendocrine axis among vertebrates: Evidence from the teleost fish, Gasterosteus aculeatus

Neuroendocrine Effects of Endocrine Disruptors in Teleost Fish

Lampreys: Biology, Conservation and Control

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