Conserved functional control, but distinct regulation, of cell proliferation in rice and <i>Arabidopsis</i> leaves revealed by comparative analysis of <i>GRF-INTERACTING FACTOR 1</i> orthologs

Shimano, Satomi; Hibara, Ken-ichiro; Furuya, Tomoyuki; Arimura, Shin‐ichi; Tsukaya, Hirokazu; Itoh, Jun-Ichi

doi:10.1242/dev.159624

Cited by 43 publications

(51 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…OsGIF1 positively regulates cell proliferation and revealed conserved functional control of MAKIBA3 ( MKB3 ) and ANGUSTIFOLIA3 ( AN3 ) in rice and Arabidopsis, respectively. A loss-of-function mutant MKB3 exhibited narrowed- and rolled-leaf phenotype ( Shimano et al, 2018 ). Overexpression of an α-expansin gene OsEXPA8 ( EXPANSIN 8 ) produced improved root system, enhanced leaf number and enlarged leaf size in rice.…”

Section: Role Of Genes In Controlling Leaf Sizementioning

confidence: 99%

Current Advances in Molecular Basis and Mechanisms Regulating Leaf Morphology in Rice

Ali

Han

2018

Front. Plant Sci.

View full text Add to dashboard Cite

Yield is majorly affected by photosynthetic efficiency. Leaves are essential structure for photosynthesis and their morphology especially size and shape in a plant canopy can affect the rate of transpiration, carbon fixation and photosynthesis. Leaf rolling and size are considered key agronomic traits in plant architecture that can subsidize yield parameters. In last era, a number of genes controlling leaf morphology have been molecularly characterized. Despite of several findings, our understanding toward molecular mechanism of leaf rolling and size are under-developed. Here, we proposed a model to apprehend the physiological basis of different genes organized in a complex fashion and govern the final phenotype of leaf morphology. According to this leaf rolling is mainly controlled by regulation of bulliform cells by SRL1, ROC5, OsRRK1, SLL2, CLD1, OsZHD1/2, and NRL1, structure and processes of sclerenchyma cells by SLL1 and SRL2, leaf polarity by ADL1, RFS and cuticle formation by CFL1, and CLD1. Many of above mentioned and several other genes interact in a complex manner in order to sustain cellular integrity and homeostasis for optimum leaf rolling. While, leaf size is synchronized by multifarious interaction of PLA1, PLA2, OsGASR1, and OsEXPA8 in cell division, NAL1, NAL9, NRL1, NRL2 in regulation of number of veins, OsCOW1, OsPIN1, OsARF19, OsOFP2, D1 and GID in regulation of phytohormones and HDT702 in epigenetic aspects. In this review, we curtailed recent advances engrossing regulation and functions of those genes that directly or indirectly can distress leaf rolling or size by encoding different types of proteins and genic expression. Moreover, this effort could be used further to develop comprehensive learning and directing our molecular breeding of rice.

show abstract

Section: Role Of Genes In Controlling Leaf Sizementioning

confidence: 99%

Current Advances in Molecular Basis and Mechanisms Regulating Leaf Morphology in Rice

Ali

Han

2018

Front. Plant Sci.

View full text Add to dashboard Cite

show abstract

“…In this cluster, GO terms associated with cell division and cytokinesis (microtubule-based movement, p = 8.6e−05) were detected. Moreover, it contained ANT clade genes of the PLETHORA family [33], GRF family genes [12], and OsGIF1/MKB3 [11], which have been described as promoters of cell proliferation in leaf primordia. Thus, Cluster 2 was expected to contain important genes related to cell proliferation in leaf primordia.…”

Section: Gene Expression Patterns During Leaf Development and Their Amentioning

confidence: 99%

“…Meanwhile, cell proliferation patterns have been reported to affect grass leaf morphology. Cell proliferation in immature tissues of leaf primordia is controlled by protein complexes encoded by two gene families, GROWTH-REGULATING FACTORS (GRFs) and GRF-INTERACTING FACTORS (GIFs) [8,9,10,11]. Changes in their protein complex composition reportedly serve as a switch for the transition from cell division to cell expansion [12].…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Analysis of Spatiotemporal Expression Patterns During Rice Leaf Development

Miya

Yoshikawa

Satō

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

Background: Rice leaves consist of three distinct regions along a proximal-distal axis, namely the leaf blade, sheath, and blade-sheath boundary region. Each region has a unique morphology and function, but the genetic programs underlying the development of each region are poorly understood. To fully elucidate rice leaf development and discover genes with unique functions in rice and grasses, it is crucial to explore genome-wide transcriptional profiles during the development of the three regions.Results: In this study, we performed microarray analysis to profile the spatial and temporal patterns of gene expression in the rice leaf using dissected parts of leaves sampled in broad developmental stages. The dynamics in each region revealed that the transcriptomes changed dramatically throughout the progress of tissue differentiation, and those of the leaf blade and sheath differed greatly at the mature stage. Cluster analysis of expression patterns among leaf parts revealed groups of genes that may be involved in specific biological processes related to rice leaf development. Moreover, we found novel genes potentially involved in rice leaf development using a combination of transcriptome data and in situ hybridization, and analyzed their spatial expression patterns at high resolution. We successfully identified multiple genes that exhibit localized expression in tissues characteristic of rice or grass leaves.Conclusions: Although the genetic mechanisms of leaf development have been elucidated in several eudicots, direct application of that information to rice and grasses is not appropriate due to the morphological and developmental differences between them. Our analysis provides not only insights into the development of rice leaves but also expression profiles that serve as a valuable resource for gene discovery. The genes and gene clusters identified in this study may facilitate future research on the unique developmental mechanisms of rice leaves.

show abstract

“…Multiple levels of regulation control the efficiency of the assembly of functional GRF/GIF complexes in vivo 17 . Loss-of-function mutations in GIF genes mimic the reduced organ size observed in GRF loss-of-function mutants or in plants overexpressing miR396 11-13, 18, 19 while overexpression of GIF promotes organ growth and can boost the activity of GRFs 12,13,15,[20][21][22] . Furthermore, simultaneous increases in the expression of Arabidopsis GRF3 and GIF1 promotes larger increases of leaf size relative to the individual genes 15 .…”

mentioning

confidence: 99%

“…We identified 10 GRFs in the wheat genome (Supplementary Figure 1A) and selected wheat GRF4 based on its homology to OsGRF4, a rice gene that promotes grain and plant growth in rice and wheat [23][24][25][26][27] . Among the three wheat GIF cofactors, we selected the closest homologue of Arabidopsis and rice GIF1 (Supplementary Figure 1B), because members of this clade have been shown to control growth in Arabidopsis, rice and maize 12,13,21,22 . We then combined GIF1 and GRF4 to generate a GRF4-GIF1 chimera including a short intergenic spacer ( Figure 1A) using primers described in Supplementary Table 1 (Supplementary Methods 1).…”

mentioning

confidence: 99%

A chimera including aGROWTH-REGULATING FACTOR(GRF) and its cofactorGRF-INTERACTING FACTOR(GIF) increases transgenic plant regeneration efficiency

Debernardi

Tricoli

Ercoli

et al. 2020

Preprint

View full text Add to dashboard Cite

Genome editing allows precise DNA manipulation, but its potential is limited in many crops by low regeneration efficiencies and few transformable genotypes. Here, we show that expression of a chimeric protein including wheat GROWTH-REGULATING FACTOR 4 (GRF4) and its cofactor GRF-INTERACTING FACTOR 1 (GIF1) dramatically increases the efficiency and speed of regeneration in wheat, triticale and rice and expands the number of transformable wheat genotypes. Moreover, GRF4-GIF1 induces efficient wheat regeneration in the absence of exogenous cytokinins, which facilitates selection of transgenic plants without selectable markers. By combining GRF4-GIF1 and CRISPR-Cas9 technologies, we were able to generate large numbers of edited wheat plants. The GRF4-GIF1 transgenic plants were fertile and without obvious developmental defects, likely due to post-transcriptional regulatory mechanisms operating on GRF4 in adult tissues. Finally, we show that a dicot GRF-GIF chimera improves regeneration efficiency in citrus suggesting that this strategy can be expanded to dicot crops.

show abstract

Conserved functional control, but distinct regulation, of cell proliferation in rice and Arabidopsis leaves revealed by comparative analysis of GRF-INTERACTING FACTOR 1 orthologs

Cited by 43 publications

References 63 publications

Current Advances in Molecular Basis and Mechanisms Regulating Leaf Morphology in Rice

Current Advances in Molecular Basis and Mechanisms Regulating Leaf Morphology in Rice

Genome-Wide Analysis of Spatiotemporal Expression Patterns During Rice Leaf Development

A chimera including aGROWTH-REGULATING FACTOR(GRF) and its cofactorGRF-INTERACTING FACTOR(GIF) increases transgenic plant regeneration efficiency

Contact Info

Product

Resources

About