The radical transformations that modern Ukrainian society is experiencing in the conditions of full-scale aggression of the Russian Federation against Ukraine and its acquisition of the status of a candidate for the EU require a proper, in-depth and comprehensive analysis of Ukraine’s humanitarian development strategies, the implementation of the European integration vector of its development. The humanitarian strategies of Ukraine’s development in the context of full membership in the European Union are studied. It is shown that they should be determined by the national interests of the entire society, ensuring the rights and freedoms of citizens, and updating the system of fundamental values of the Ukrainian people. Paradigmatic European values include Ukrainian civilizational identity (spirituality), state sovereignty and territorial integrity of Ukraine, high level of human development, democratic society, full standards of living, gender equality, etc. The focus of the research is: artifacts of totalitarian society and their overcoming; European experience and the Ukrainian way in forming a system of values; civil society and state institutions; synergy of interaction in the European integration context; formation of collective memory and rethinking of Ukraine’s past in a European perspective. Special attention is paid to the dynamics of the processes of democratization and decommunization, cultural and linguistic policy, interethnic and interreligious relations, etc.