Constant rate infusion of glucagon as an emergency treatment for hypoglycemia in a domestic ferret (Mustela putorius furo)

Bennett, Katarina; Gaunt, M. Casey; Parker, Dennilyn L.

doi:10.2460/javma.246.4.451

Cited by 13 publications

(4 citation statements)

References 15 publications

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“…The use of constant‐rate infusion of glucagon has been described as an emergency treatment for severely hypoglycaemic ferrets that are not responsive to dextrose. A dose of 15 to 40 ng/kg/min proved effective in increasing blood glucose concentrations (Bennett and others 2015).…”

Section: Common Tumours Seen In Ferretsmentioning

confidence: 99%

Guide to diagnosing and treating neoplasia in ferrets

Dias¹

2022

In Practice

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Background: Statistics for the actual incidence of neoplasia in pet ferrets are not currently available; however, multiple case reports of different types of neoplasia in this species are described in the literature. The majority of tumours are seen in animals older than three years of age, and multiple types of neoplasia can occur in the same ferret.Aim of the article: This article provides an overview of the most common ferret neoplasms seen by general veterinary practitioners, and aims to help practitioners approach these cases with more confidence. The endocrine, haemolymphatic and integumentary systems are most commonly affected, with adrenocortical tumours and insulinoma at the top of the list.

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Section: Common Tumours Seen In Ferretsmentioning

confidence: 99%

Guide to diagnosing and treating neoplasia in ferrets

Dias¹

2022

In Practice

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“…Surgery can also be pursued with published mean survival times of 668 days with a partial pancreatectomy versus 186 days with medical management alone (Weiss et al 1998). One case report details the successful dose of 15 ng/kg/min glucagon constant rate infusion at in a 3-year-old female domestic ferret with an insulinoma (Bennett et al 2015). In addition to numerous case reports in ferrets, there is one report of a pre mortem diagnosis and treatment of an insulinoma in a 5-year-old male guinea pig that was treated medically with a starting dose of 5 mg/kg diazoxide orally every 12 hours, eventually increasing to 25 mg/kg orally every 12 hours.…”

Section: Insulinomasmentioning

confidence: 99%

Pathophysiology and aetiology of hypoglycaemic crises

Morgan¹,

Cortes²,

Murphy³

2018

J of Small Animal Practice

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Hypoglycaemia is a common, life-threatening complication that occurs as a component of a wide variety of disease processes. Despite its frequent occurrence, information concerning the aetiology, characteristics and outcomes of hypoglycaemic crises in veterinary medicine is limited. This review summarises the current understanding of the pathophysiology of hypoglycaemia, the body's counterregulatory response, underlying aetiologies, diagnosis and treatment. Disease mechanisms are discussed and published evidence in veterinary literature regarding prognostic indicators, prevalence, diagnosis and treatment is examined for hypoglycaemia-related disease processes including insulinoma, glucose-lowering toxins and medications.

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“…A dosage of 15 to 40 ng/ kg/min (as extrapolated from data in dogs and cats) proved effective in increasing blood glucose concentrations and alleviating the clinical signs in an elderly ferret that did not respond sufficiently to other types of therapy. 63 Owners are advised to monitor their ferrets closely for signs of hypoglycemia and feed the ferret immediately if mild signs of hypoglycemia are noted. In the event of a seizure or comatose condition, the owner is advised to give a carbohydrate-rich or protein-rich liquid food to the ferret.…”

Section: Medical Treatmentmentioning

confidence: 99%