Constipation, breath methane, and orocecal transit time for a bean meal test

The Impact of Small Intestinal Bacterial Overgrowth on the Growth of Children and Adolescents

“…Samples of exhaled air were collected at 15, 30, 45, 60, 90, 120, 150 and 180 minute intervals after lactulose ingestion. 4,[13][14][15][16][17] The no rebreathing valve set up device designed by QuinTron Instrument Company Inc. (Menomonee Falls, Wisconsin, USA) was used to collect exhaled air samples. The device has a valve that allows air to pass in one direction only.…”

“…Non-H 2 producers were considered as those patients who did not present a minimum elevation of 10 ppm H 2 in exhaled air after lactulose ingestion in any of the samples. [12][13][14][15][16][17] For the analysis of the results, the SigmaPlot 12.0 software (Systat Software Inc., USA) and Epi-Info version 6 (Centers for Disease Control and Prevention, USA) were used, using setting 5% as the level to reject the null hypothesis. The chisquare test was used for the analysis of categorical variables.…”

“…[2][3][4][5] It may also be found in functional gastrointestinal disorders such as irritable bowel syndrome, functional abdominal pain, and functional constipation. [6][7][8][9][10][11][12][13] SIBO is still associated with poverty and may favor nutrient malabsorption as part of environmental enteropathy. [14][15][16][17] Height impairment has been noted in children with SIBO living in underdeveloped countries when interpreting the concentrations of hydrogen (H 2 ) and methane (CH 4 ) in the lactulose breath test.…”

“…23 In our experience, lactulose was always used for SIBO research using the breath test. [13][14][15][16][17][18]22 In one of these articles 17 , both glucose and lactulose tests were performed, showing that H 2 production with glucose was very low, which presumably underestimated the prevalence of SIBO in the study population. 17 In this context, in another consensus published in 2017, it was recommended to use both lactulose and glucose as a substrate to be used in a study on SIBO using the breath test.…”

Effectiveness of Trimethoprim‐Sulfamethoxazole and Metronidazole in the Treatment of Small Intestinal Bacterial Overgrowth in Children Living in a Slum

“…(JPGN 2013;57: 316-318) S mall intestinal bacterial overgrowth (SIBO) is an intestinal microflora imbalance with abnormally high bacterial counts in the small intestine, which may be associated with a wide clinical spectrum ranging from the absence of clinical features or mild and unspecific intestinal symptoms to severe malabsorption (1,2). SIBO may be associated with diverse clinical conditions, such as chronic diarrhea (3,4), malnutrition (5), intestinal failure (2,(6)(7)(8), and functional gastrointestinal disorders (9)(10)(11)(12), and with children living in areas with poor sanitation, such as in urban slums (13,14).…”