2007
DOI: 10.1248/cpb.55.1649
|View full text |Cite
|
Sign up to set email alerts
|

Constituents of Crinoidea. 5. Isolation and Structure of a New Glycosyl Inositolphosphoceramide-Type Ganglioside from the Feather Star Comanthina schlegeli

Abstract: In our continuing research on biologically active glycosphingolipids (GSLs) from echinoderms, a series of studies on the isolation and structural elucidation of biologically active GSLs have been performed in our laboratory. [1][2][3] In the study of the GSLs of the crinoidea, we reported on the isolation and structural elucidation of cerebrosides, 4) inositolphosphoceramide, 5) and the glycosyl inositolphosphoceramide-type gangliosides 6,7) from the feather star Comanthus japonica. Continuing the preceding st… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
14
0

Year Published

2012
2012
2020
2020

Publication Types

Select...
4
3
2

Relationship

0
9

Authors

Journals

citations
Cited by 17 publications
(14 citation statements)
references
References 12 publications
0
14
0
Order By: Relevance
“…For gangliosides of echinoderms [ 38 42 ], there is no systematic short-hand nomenclature. They show structural features uncommon to mammalian gangliosides, such as sialic acid residues within the oligosaccharide moieties (e.g., LG-2, Figure 5 ), α 2,11-linked sialic acids (e.g., LLG-5, Figure 5 ), sialic acid methylation or sulfation, or a glycosyl inositolphosphoceramide core, for example, [ 43 , 44 ]. In cultured neurons, echinodermal gangliosides show neuritogenic and growth-inhibitory activities.…”
Section: Structure and Nomenclaturementioning
confidence: 99%
“…For gangliosides of echinoderms [ 38 42 ], there is no systematic short-hand nomenclature. They show structural features uncommon to mammalian gangliosides, such as sialic acid residues within the oligosaccharide moieties (e.g., LG-2, Figure 5 ), α 2,11-linked sialic acids (e.g., LLG-5, Figure 5 ), sialic acid methylation or sulfation, or a glycosyl inositolphosphoceramide core, for example, [ 43 , 44 ]. In cultured neurons, echinodermal gangliosides show neuritogenic and growth-inhibitory activities.…”
Section: Structure and Nomenclaturementioning
confidence: 99%
“…New classes of gangliosides have been found in echinoderms, such as sea cucumbers [ 23 , 24 , 25 ], starfish [ 26 , 27 , 28 , 29 , 30 , 31 ], sea urchins [ 32 , 33 , 34 ], and feather stars [ 35 ], and many of these echinodermatous gangliosides (EGs) also exhibited neuritogenic activity, some of which exceeded that of mammalian GM1 [ 36 , 37 ]. In contrast to mammalian gangliosides, EGs contain partially modified sialic acid residues and their unique oligomers.…”
Section: Introductionmentioning
confidence: 99%
“…More recently, a 9-O-methylated variant of Neu5Ac, Neu5Ac9Me, was also found. 47 In the period between 1976 and 1990 much attention was paid to 8-O-sulfated sialic acids (see Table 1) being present in glycoproteins (see Section 8.1) and glycolipids (see Section 8.2). Here, the group of Kochetkov and coworkers at the Academy of Sciences in Moscow (Russia), working on sialoglycolipids of sea urchin species (Neu5Ac8S, Neu5Gc8S; e.g., ref.…”
Section: Other Natural Sialic Acidsmentioning
confidence: 99%