Constitutional thinness: body fat metabolism and skeletal muscle are important factors

Invited Letter to Editor in response to: Constitutional thinness: body fat metabolism and skeletal muscle are important factors

“…As also pointed out by our analysis, most of the included clinical trials defined a threshold of thinness in their inclusion criteria using BMI cut-offs and less frequently the percentage of body fat. In his recent and relevant letter to the Editor, Dr Maffetone (2) highlighted the quality and pertinence of our work, suggesting, however, to reinforce the consideration of both body fat metabolism (pointing moreover the limitation induced by the use of BMI only) and skeletal muscle strength that might be of importance when it comes to individuals with CT.…”

“…Our conclusions and the constructive comment from Dr Maffetone call for further physiological and functional investigations of both adipose and muscle tissues in individuals with CT, to better understand and diagnose this condition and hopefully propose appropriate and effective intervention strategies favouring weight gain in this population. Mélina Bailly 1,2 , Natacha Germain 2,3 , Bogdan Galusca 2,3 , Daniel Courteix 1 , David Thivel 1 and Julien Verney 1…”