Resolving patterns of tropical climate variability during and since the last glacial maximum (LGM) is fundamental to assessing the role of the tropics in global change, both on ice-age and sub-millennial timescales. Here, we present a 10 Be moraine chronology from the Cordillera Carabaya (14.3°S), a sub-range of the Cordillera Oriental in southern Peru, covering the LGM and the first half of the last glacial termination. Additionally, we recalculate existing 10 Be ages using a new tropical high-altitude production rate in order to put our record into broader spatial context. Our results indicate that glaciers deposited a series of moraines during marine isotope stage 2, broadly synchronous with global glacier maxima, but that maximum glacier extent may have occurred prior to stage 2. Thereafter, atmospheric warming drove widespread deglaciation of the Cordillera Carabaya. A subsequent glacier resurgence culminated at ~16,100 yrs, followed by a second period of glacier recession. Together, the observed deglaciation corresponds to Heinrich Stadial 1 (HS1: ~18,000-14,600 yrs), during which pluvial lakes on the adjacent Peruvian-Bolivian altiplano rose to their highest levels of the late Pleistocene as a consequence of southward displacement of the inter-tropical convergence zone and intensification of the South American summer monsoon. Deglaciation in the Cordillera Carabaya also coincided with the retreat of higher-latitude mountain glaciers in the SouthernHemisphere. Our findings suggest that HS1 was characterised by atmospheric warming and indicate that deglaciation of the southern Peruvian Andes was driven by rising temperatures, despite increased precipitation. Recalculated 10 Be data from other tropical Andean sites support this model. Finally, we suggest that the broadly uniform response during the LGM and termination of the glaciers examined here involved equatorial Pacific sea-surface temperature anomalies and propose a framework for testing the viability of this conceptual model. 1 Introduction As the energetic powerhouse of the globe, the tropics (23°N-23°S) are the principal source of heat energy and water vapour for the climate system andthus represent a fundamental and dynamic component of global climate (Cane, 1998; Pierrehumbert, 1999; Visser et al., 2003). Today, the tropical influence is exemplified by the El Niño