Constriction of the ductus arteriosus, severe right ventricular hypertension, and a right ventricular aneurysm in a fetus after maternal use of a topical treatment for striae gravidarum

Abstract

Fetal constriction of the ductus arteriosus is a complication of maternal non-steroidal anti-inflammatory drug use and polyphenol-rich food intake. It is unclear as to whether polyphenol-containing topical treatments have similar effects. We present a case of fetal constriction of the ductus arteriosus, severe right ventricular hypertension, and a right ventricular aneurysm associated with maternal use of a topical treatment for striae gravidarum.

Reply on “Constriction of the ductus arteriosus, severe right ventricular hypertension, and a right ventricular aneurysm in a fetus after maternal use of a topical treatment for striae gravidarum”

“…We read with great interest the brief report of Dr Hayes concerning the unfortunate fetal constriction of the ductus arteriosus of a single male infant that the author associated with use of topically applied Bio-Oil ® 1 . This is very surprising for us as Bio-Oil ® has a long, safe history of use for the treatment of scars and striae and is widely used – it has been marketed in South Africa for 29 years and globally for 14 years, and last year alone over 19 million units were sold.…”