Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC
Lu Wang,
Ye He,
Yijiang Bai
et al.
Abstract:Purpose
Metabolic reprogramming is currently considered a hallmark of tumor and immune development. It is obviously of interest to identify metabolic enzymes that are associated with clinical prognosis in head and neck squamous cell carcinomas (HNSCC).
Methods
Candidate genes were screened to construct folate metabolism scores by Cox regression analysis. Functional enrichment between high- and low-folate metabolism groups was explored by GO, KEGG, … Show more
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