Information systems in the health field should be communicating to foster cooperation of professionals in the health process centered on the patient, and to assist in medical decision. Therefore, communication through computer tools and the creation of computerized patient records require the use of semantic repositories whose control is required. Indeed, the sharing of patient data principle is needed particularly because of the development of medical knowledge, which helps to segment the expertise, skills and roles of players. The application of this principle allows greater coordination between professionals and requires appropriate and scalable information systems. The necessary data sharing and the development of information systems strongly emphasizes the issue of semantic interoperability of health systems and management repositories. However, if, in the context of the interoperability of information systems, choice, maintenance and the use of semantic standards are necessary conditions, the behavior of players and practices of evaluation procedures are nevertheless essential component for proper functioning.