Recently, the world has seen a tendency of reinforced concrete housing construction industrialization. Russia has gained extensive experience in large-panel housing construction, which helps to find optimal structural solutions, but new solutions lead to the need for additional study. Modern software systems allow you to build volumetric models of a building, taking into account physical non-linearity, which helps to take into account the actual distribution of efforts between the elements. At the same time, to build the correct model of a large-panel building, the flexibility of joints between them is required. The flexibility is calculated by online tests the results of which are used to build the future model of a building in the process of its designing. The calculation model of a building gives an approximate estimate of structural behavior and the degree of its accuracy depends on the correct selection of the initial premises. This article estimates the numerical model of a large-panel building by comparing it with the results of direct observations of shear movements in the vertical joints of the most loaded walls of a building under construction. The observations were carried out on a 26-story large-panel building with a cross structural system with self-supporting external longitudinal walls. Vertical joints are monolithic reinforced concrete with the use of dowels with cable loop transverse reinforcement.In addition, estimation of forces at the joints is also given. In general, we may conclude that the calculation model of a large-panel building is applied correctly using elastic-flexible connections with limiting ultimate forces for vertical joints modeling.The modeling part of the study is performed using a finite element model taking into account the magnitude of the joints flexibility and the actual stiffness of the building structural elements.The results of the study can be used in modeling, calculation and design of large-panel buildings, and they provide new scientific knowledge about the operation of buildings of this type.