Construction of a Au@MoS₂ composite nanosheet biosensor for the ultrasensitive detection of a neurotransmitter and understanding of its mechanism based on DFT calculations

Abstract

An electrochemical biosensor based on Au@MoS2 composite nanosheets was successfully prepared for the high-sensitivity detection of dopamine.

Biophysical and computational analyses of interaction of 2D MoS2 nanosheets with human haemoglobin coupled with NIR activated photothermal therapy

“…14,15 Due to its large surface area, 2D MoS 2 based biosensors and drug delivery systems have also been developed. 8,9,16 2D MoS 2 NSs have high absorbance in the near-infrared region (NIR) and hence they have been utilized for photothermal therapy (PTT) of cancer. 17,18 PTT is a minimally invasive technique that uses NIR laser to irradiate nanoprobes, resulting in heat generation for the localized destruction of malignant tissues.…”

“…6 They display exceptional properties as compared to their bulk counterparts due to their large diameter to length ratio. 7 Isolation of graphene in 2004 triggered the discovery of other 2D nanomaterials, such as boron nitride, transition metal dichalcogenides (TMDCs: MoS 2 , MoSe 2 , WS 2 , and WSe 2 ), and transition metal oxides (TMOs: MoO 3 8,9 and MnO 2 ) and the recent ones such as phosphorene, germanene and silicene. 10 The 2D TMDCs are notable among these nanoparticles due to their size-dependent band gap, tunable crystal structure and desirable electrical, chemical and optical properties.…”

“…14,15 Due to its large surface area, 2D MoS 2 based biosensors and drug delivery systems have also been developed. 8,9,16…”

MoS2-Carbon Nanodots as a New Electrochemiluminescence Platform for Breast Cancer Biomarker Detection

“…MoS 2 -NS is clearly interesting in the development of new biosensors not only for the possibility to functionalize its surface with thiolated molecules [ 37 , 38 , 39 , 40 ] but also due to the possibility of developing new platforms with increased relative surface area and, therefore, with higher sensitivity. There are several biosensors reported in the literature based on the use of this nanomaterial [ 41 , 42 , 43 , 44 , 45 , 46 ], but it is still an emerging area that needs to be explored further. Hence, in this work, we decided to go a step forward and use MoS 2 -NS in combination with CDs for the development of a new electrochemiluminescence aptasensor for the detection of a breast cancer biomarker, HER2 protein.…”

Comparison of Kinetics of Adsorption of Permanganate on Co-Al-Layered Double Hydroxide and MoS2 Nanocompounds

“…MoS 2 shows polytypism and has three various configurations like 1T, 22 2H 23 and 3R 24 that represent its trigonal, hexagonal and rhombohedral arrangements, respectively and among them 2H is the most stable thermodynamic form of MoS 2 . 23 MoS 2 possesses many applications such as solid lubricant, 25 biosensor, 26 gas sensor, 27 catalyst, 28 supercapacitor 29 and for tissue engineering, 30 electronic and optoelectronic devices, 31 energy storage, 32 solar energy storage, 33 and biomedical applications. 34 Potassium permanganate (KMnO 4 ), known as "Condy's Crystal", is a strong oxidizing inorganic compound and has many applications like medical uses, 35 water treatment process 36 , analytical uses 37 and synthesis of organic compounds 38 in laboratories and industry.…”