Construction of a computational MDCT model for simulations of the detector signals

Wang, Chuyan; Lin, Xiao; Li, Hongming; Fu, Jianwei; Zhuo, Weihai; Liu, Haikuan

doi:10.1016/j.radmp.2023.02.003

Cited by 1 publication

(1 citation statement)

References 26 publications

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“…260. In our previous study (Wang et al 2023), the phantom was scanned using a 128-slice CT scanner (uCT-760, Shanghai United Imaging Healthcare Co., LTD), and its DICOM file was imported into the software of 3DSlicer® (Kitware, USA) to build the digital phantom after delineating the organs or tissues and adding their chemical components and densities. The digital phantom is composed of 167 × 167 × 198 voxels with a resolution of 0.3 cm × 0.3 cm × 0.5 cm.…”

Section: Phantommentioning

confidence: 99%

Radiation levels outside a patient undergoing ¹⁷⁷Lu-PSMA radioligand therapy

Li,

Liu,

Zhang

et al. 2024

J. Radiol. Prot.

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Understanding the spatial distribution of radiation levels outside of a patient undergoing 177Lu radioligand therapy is not only helpful for conducting correct tests for patient release, but also useful for estimation of its potential exposure to healthcare workers, caregivers, family members, and the general public. In this study, by mimicking the 177Lu-PSMA radioligand therapy for prostate cancers in an adult male, the spatial distribution of radiation levels outside of the phantom was simulated based on the Monte Carlo software of PHITS, and verified by a series of measurements. Moreover, the normalized dose rates were further formulized on the three transverse planes representing the heights of pelvis, abdomen and chest. The results showed that the distributions of radiation levels were quite complex. Multi-directional and multi-height measurements are needed to ensure the external dose rate to meet the release criteria. In general, the radiation level was higher at the horizontal plane where the source was located, and the levels in front and behind of the body were higher than those of the left and right sides at the same height. The ratio of simulated dose rates to measured ones ranged from 0.82 to 1.19 within 1 m away from the body surface in all directions. Based on the established functions, the relative root mean square deviation (RRMSD) between the calculated and simulated values were 0.21, 0.25 and 0.23 within a radius of 1 m on the pelvis, abdomen and chest transverse planes, respectively. It is expected that the results of this study would be helpful for guiding the test of extracorporeal radiation to determine the patient’s release, and of benefit to estimate the radiation exposure to others.

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Section: Phantommentioning

confidence: 99%