2017
DOI: 10.3892/mmr.2017.7172
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Construction of a recombinant pIRES2-EGFP-ARTS plasmid and its effect on LX-2 cells

Abstract: The inhibition of the activation of hepatic stellate cells (HSCs) and the induction of their apoptosis have been investigated as potential strategies to counteract the development and progression of liver fibrosis. Previous research has suggested that apoptosis-related protein in the transforming growth factor-β signaling pathway (ARTS) may serve a significant role in numerous cell types; however, little is known regarding its roles in HSCs. Total RNA was extracted from LX-2 cells, and the human full-length AR… Show more

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