Construction of a traditional Chinese medicine syndrome-specific outcome measure: the Kidney Deficiency Syndrome questionnaire (KDSQ)

Chen, Run Qiu; Wong, Chit Ming; Lam, Tai Hing

doi:10.1186/1472-6882-12-73

Cited by 30 publications

(21 citation statements)

References 25 publications

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“…In our results, the constitution of yang-xu was significantly correlated with bladder problems, muscle/joint problems, depressive mood, and heart discomfort in the menopausal symptoms. These symptoms were similar to the 4 factors revealed by Chen et al [27] as the kidney-yang deficiency syndrome which included kidney-qi deficiency, deficiency cold, impaired kidney orifices, and abnormal urine excretion. We only focus on the main menopausal symptoms of menopausal women in our study to give a more simplified constitution differentiation We can infer that these symptoms of yang-xu constitution are predominate in postmenopausal women.…”

Section: Discussionsupporting

confidence: 60%

“…For example, German women suffer more from kidney yang deficiency, whereas Chinese women suffer more from kidney yin deficiency syndrome [33]. Chen et al [27] further constructed models to test and validate the premise that the menopausal syndrome could be either kidney yin and kidney yang. Borud et al [34] performed an Acuflash study to evaluate the effect of TCM acupuncture on postmenopausal vasomotor symptoms, and found that 50% of the participants were diagnosed with kidney yin xu as their primary syndrome.…”

Section: Discussionmentioning

confidence: 99%

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Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Chen

Hwang

2018

Complement Med Res

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Objective: The aim of this study was to assess the correlation between the body constitution and menopausal symptoms in climacteric women. Methods: This cross-sectional study recruited 427 women aged 40-60 years from the hospital and nearby community. In addition to filling out a questionnaire on menopause rating scale - Traditional Chinese version, the participants completed the body constitution questionnaire. This classifies a person to 1 or more of 3 imbalanced constitutional types, which are yin-xu, yang-xu and stasis-stagnation. We constructed logistic regression models to estimate probabilities of the menopausal symptoms among climacteric women presenting with various menopausal status and differing body constitutions. Results: The frequency and scores of the yin-xu, yang-xu, and stasis-stagnation constitutions were significantly higher in perimenopausal and postmenopausal than premenopausal women. Compared to the non-constitution women, the odds ratio of having hot flushes, sleeping disorders, sexual problems, irritability, and anxiety were significantly higher with the yin-xu constitution. The women with a yang-xu constitution had significantly higher odds ratios for having bladder problems, muscle and joint problems, depressive mood, and heart discomfort. Symptoms of heart discomfort, physical and mental exhaustion, and sleeping disorders were correlated to the stasis-stagnation constitution. Conclusion: With the additional key symptoms related to the 3 constitutional types, physicians performing traditional Chinese medicine (TCM) are able to diagnose the menopausal syndrome more accurately. Integrating menopausal symptoms with TCM constitutional theory will contribute to a more rapid diagnosis and treatment of menopausal syndrome.

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Section: Discussionsupporting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Chen

Hwang

2018

Complement Med Res

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“…Its symptoms include pain in the back or the knees, forgetfulness, tidal fever, night sweating, dizziness, tinnitus, insomnia, thirst at night, etc. [11]. In the Orient, Yukmijihwang decoction has been used typically for more than a thousand years for the treat ment of this syndrome.…”

Section: Discussionmentioning

confidence: 99%

Study on the Single Dose Toxicity of ShinEumHur Pharmacopuncture Injected into the Muscles of Rats

Jeong

Cha

Lee

et al. 2016

Journal of Pharmacopuncture

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Objectives:This study was carried out to analyze the single dose toxicity of ShinEumHur (SEH) pharmacopuncture injected into the muscles of Sprague-Dawley rats.Methods:The SEH pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (K-GMP). After the mixing process with sterile distilled water had been completed, the pH was controlled to between 7.0 and 7.5. All experiments were conducted at Biotoxtech, an institution authorized to perform non-clinical studies under the Good Laboratory Practice (GLP) regulations. Sprague-Dawley rats were chosen for the pilot study. Doses of SEH pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. We examined the survival rate, weights, clinical signs, mean hematology parameters, mean clinical chemistry, necropsy and histopathological findings.This study was conducted under the approval of the Institutional Animal Ethics Committee.Results:No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues.Conclusion:The above findings suggest that treatment with SEH pharmacopuncture is relatively safe. Further studies on this subject are needed to yield more concrete evidence.

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“…Symptoms of kidney-yin deficiency Zheng fall into the category of "heat". These include sore waist and knees, skelasthenia, vertigo and tinnitus, insomnia and dreaminess, postcoital protrusion or impotence or nocturnal emission in man, hypomenorrhea or menostasis even uterine bleeding in woman, emaciation, feverish night sweating, burning sensation of five centers, dry pharynx and red cheeks, juvenile leukotrichia, somniloquence and bruxism, frequency of micturition, dark yellow urine, dry stool, red tongue with sparse saliva, rapid and thready pulse [33,35,36].…”

Section: Differentiation From Liver Cancer With Other Zheng Classificmentioning

confidence: 99%

Liver Cancer: Zheng Classification of Qi Stagnation and Blood Stasis

Guan¹,

He²

2014

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There is a long history of using traditional Chinese medicine in the treatment of liver cancer and other malignnancies. The classification of Qi stagnation and blood stasis (QSBS) is the most common Zheng in liver cancer. This Zheng is frequently encountered in liver cancers falling into the pathological category of massive type. QSBS is the principal mechanism for a tumor to develop. Liver cancer with QSBS Zheng has characteristic clinical manifestations. Evidence from ex vivo, in vivo and clinical studies has been reported for the identification and management of liver cancer with QSBS Zheng. This article reviews evidence-based study advances of QSBS Zheng, the most common Zheng encountered in liver cancer.

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Construction of a traditional Chinese medicine syndrome-specific outcome measure: the Kidney Deficiency Syndrome questionnaire (KDSQ)

Cited by 30 publications

References 25 publications

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Study on the Single Dose Toxicity of ShinEumHur Pharmacopuncture Injected into the Muscles of Rats

Liver Cancer: Zheng Classification of Qi Stagnation and Blood Stasis

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