Construction of an antibacterial low-defect hybrid layer by facile PEI electrostatic assembly promotes dentin bonding

Lei, Yuqing; Xu, Jiajia; Pan, Mengqi; Chen, Yadong; Li, Xiaojun; Zhu, Weipu; Shu, Chang; Fang, Tianxiang; Liao, Hongyu; Luo, Qiaojie

doi:10.1039/d2tb01683d

Cited by 4 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consistent with our previous reports (Xu et al 2021; Lei et al 2022; Shu et al 2022), the treatment of the Ca 2+ or Cu 2+ solution significantly decreased water sorption (Fig. 2A).…”

Section: Discussionsupporting

confidence: 93%

“…These surface properties negatively affect adhesive infiltration and thus bonding effectiveness. In our previous studies, induced by these anionic groups, numerous CaF 2 (Xu et al 2021) or amorphous calcium phosphate (ACP) nanoparticles (Shu et al 2022) or stable polyelectrolyte electrostatic complex (Lei et al 2022) are rapidly formed to mask these groups, which dehydrate the DDM interface and reconstruct the DDM into a robust porous structure. Through converting the negative role of the polar groups in the DDM interface into a positive one, these bonding strategies indicate the core role of the hydrated DDM interface in dentin bonding.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Release of Interface Confined Water Significantly Improves Dentin Bonding

Pan

et al. 2023

J Dent Res

Self Cite

View full text Add to dashboard Cite

Water residue and replacement difficulty cause insufficient adhesive infiltration in demineralized dentin matrix (DDM), which produces a defective hybrid layer and thus a bonding durability problem, severely plaguing adhesive dentistry for decades. In this study, we propose that the unique properties of a highly hydrated interface of the porous DDM can give rise to 1 new type of interface, confined liquid water, which accounts for most of the residue water and may be the main cause of insufficient infiltration. To prove our hypothesis, 3 metal ions with increasing binding affinity and complex stability (Na+, Ca2+, and Cu2+) were introduced respectively to coordinate negatively charged groups such as -PO43−, -COO− abundant in the DDM interface. Strong chelation of Ca2+ and Cu2+ rapidly released the confined water, significantly improving penetration of hydrophobic adhesive monomers, while Na+ had little effect. A significant decrease of defects in the hybrid layer and a much decreased modulus gap between the hybrid layer and the adhesive layer greatly optimized the microstructure and micromechanical properties of the tooth–resin bonding interface, thus improving the effectiveness and durability of dentin bonding substantially. This study paves the way for a solution to the core scientific issue of contemporary adhesive dentistry: water residue and replacement in dentin bonding, both theoretically and practically.

show abstract

“…Consistent with our previous reports (Xu et al 2021; Lei et al 2022; Shu et al 2022), the treatment of the Ca 2+ or Cu 2+ solution significantly decreased water sorption (Fig. 2A).…”

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Release of Interface Confined Water Significantly Improves Dentin Bonding

Pan

et al. 2023

J Dent Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…The bonding strategy based on the rapid dehydration reconstruction of the hydrated interface can remove the confined water, significantly improve adhesive infiltration and thus allow for the construction of a defect-low hybrid layer or even antibacterial defect-low hybrid layer. [23][24][25][26] These reports suggest that the hydrated DDM interface may play the most prominent role in dentin bonding. It is not only the root cause of unsatisfactory bonding effects that result in current massive clinical issues, but may also be key to solving many problems associated with clinical bonding practices.…”

Section: Introductionmentioning

confidence: 99%