We show that application of the double clad hollow core fiber (DCHCF) significantly affects efficiency of collecting a two photon fluorescence signal. In our approach we propose a new construction of the hollow core double clad fiber which can be used to send simultaneously an ultrafast signal through the single-mode air core and collect the florescence signal through a multimodal clad. The presented fiber has a dispersion equal to 5.13 ps/nm km and losses 0.5 dB/m in the range of 800 nm. In the wavelengths range between 770 to 850 nm the fiber is endlessly single mode with higher order modes HOM's losses above 17 dB/m. The use of such a fiber allows elimination of prevalent precompensation dispersion systems and considerably simplifies the two photon fluorescence endoscopy setup.