At present, the construction of online courses is an important content in the process of educational informatization. At present, there are two problems in the construction of online courses: from the teaching point of view, the design of teaching activities and teaching processes in online courses is not enough, and the teaching effect is not good. Technically, the development of most courses is basically one-off and cannot be updated quickly. Due to the small scale, limited access and strong pertinence of SPOC, it has obvious advantages to implement the online and offline mixed teaching mode of college English based on SPOC in college English teaching. This paper mainly studies the research and analysis of English online courses based on the hybrid real-time synchronization algorithm. This paper combines OFDM synchronization algorithm with SPOC hybrid algorithm teaching to analyze and study it. According to the research, the influence of English online teaching course is very great, and the effect is more obvious than that of traditional teaching.