2022
DOI: 10.1097/md.0000000000029107
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Construction of miRNA-regulated drug-pathway network to screen drug repurposing candidates for multiple sclerosis

Abstract: Given the high disability rate of multiple sclerosis (MS), there is a need for safer and more effective therapeutic agents. Existing literature highlights the prominent roles of miRNA in MS pathophysiology. Nevertheless, there are few studies that have explored the usefulness of existing drugs in treating MS through potential miRNA-modulating abilities.The current investigation identifies genes that may exacerbate the risk of MS due to their respective miRNA associations. These findings were then used to deter… Show more

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