Construction of single-molecule counting-based biosensors for DNA-modifying enzymes: A review

Zhang, Qian; Hu, Juan; Li, Dong-ling; Qiu, Jian-Ge; Jiang, Bing-Hua; Zhang, Chun-yang

doi:10.1016/j.aca.2024.342395

Analytica Chimica Acta

2024

DOI: 10.1016/j.aca.2024.342395

|View full text |Cite

Construction of single-molecule counting-based biosensors for DNA-modifying enzymes: A review

Qian Zhang,

Juan Hu,

Dong-ling Li

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 160 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Recent Advance in Single-Molecule Fluorescent Biosensors for Tumor Biomarker Detection

Zhang,

Liu,

Qiao

et al. 2024

Biosensors

View full text Add to dashboard Cite

The construction of biosensors for specific, sensitive, and rapid detection of tumor biomarkers significantly contributes to biomedical research and early cancer diagnosis. However, conventional assays often involve large sample consumption and poor sensitivity, limiting their further application in real samples. In recent years, single-molecule biosensing has emerged as a robust tool for detecting and characterizing biomarkers due to its unique advantages including simplicity, low sample consumption, ultra-high sensitivity, and rapid assay time. This review summarizes the recent advances in the construction of single-molecule biosensors for the measurement of various tumor biomarkers, including DNAs, DNA modifications, RNAs, and enzymes. We give a comprehensive review about the working principles and practical applications of these single-molecule biosensors. Additionally, we discuss the challenges and limitations of current single-molecule biosensors, and highlight the future directions.

show abstract

Recent Advance in Single-Molecule Fluorescent Biosensors for Tumor Biomarker Detection

Zhang,

Liu,

Qiao

et al. 2024

Biosensors

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Construction of single-molecule counting-based biosensors for DNA-modifying enzymes: A review

Cited by 1 publication

References 160 publications

Recent Advance in Single-Molecule Fluorescent Biosensors for Tumor Biomarker Detection

Recent Advance in Single-Molecule Fluorescent Biosensors for Tumor Biomarker Detection

Contact Info

Product

Resources

About