Consumer Healthcare Products Association response to Major et al., “Trends in rates of acetaminophen‐related adverse events in the United States”, Pharmacoepidemiology &amp; Drug Safety, May 2016, 25: 590–8

Sirois, Jay E.

doi:10.1002/pds.4129

Cited by 2 publications

(2 citation statements)

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“…We are not aware of other published reports on secular trends in the prevalence of acetaminophen use over the 4‐g limit. Declines in population rates of acetaminophen‐related calls to poison centres and hospital visits (up until 2012) have been reported, which have been variously interpreted to reflect increases or decreases in relation to product sales. These findings are not directly comparable with ours, because simply exceeding the 4‐g daily limit is not necessarily associated with medical consequences or symptoms—these are usually seen with much higher doses—or with concern sufficient to trigger a call to a poison‐control centre.…”

Section: Discussionmentioning

confidence: 99%

“…Reports of unintentional overdosing of acetaminophen led the US Food and Drug Administration (FDA) to convene an Advisory Committee on the subject in 2009 . Since that time, some analyses have reported declines in acetaminophen‐related calls to poison centres and hospital visits . It is not known how consumers' use of acetaminophen medications may have changed.…”

Section: Introductionmentioning

confidence: 99%

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Five‐year trends in acetaminophen use exceeding the recommended daily maximum dose

Kaufman

Kelly

Battista³

et al. 2019

Brit J Clinical Pharma

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Temporal patterns of acetaminophen use exceeding the recommended daily maximum dosage of 4 g over a 5-year period (4/1/2011-3/31/2016) were evaluated in an online 1-week diary study of 14 434 adult acetaminophen users who also reported acetaminophen use in the previous month. Specific medications taken were identified by list-based prompting; respondents were not required to know their medications contained acetaminophen. Details of use were recorded daily; total daily dosage was determined programmatically. Prevalence of >4 g use over time was modelled and tested for linear changes. The overall prevalence of >4 g use (6.3% of users and 3.7% of usage days) did not change over the 5 years: odds ratio (OR) persons, 1.02 (95% CI, 0.98-1.09); OR days, 0.98 (0.92-1.05). Deviations from label directions were largely unchanged, though concomitant use increased slightly. Thus, over a recent 5-year period, there was no evidence of change in how often acetaminophen use exceeded the labelled maximum daily dose.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Five‐year trends in acetaminophen use exceeding the recommended daily maximum dose

Kaufman

Kelly

Battista³

et al. 2019

Brit J Clinical Pharma

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Evaluation of pharmacist interventions as part of a multidisciplinary pain management team

Barseghyan

Nazaryan

Simonyan

2022

NAMJ

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Pharmacists have an important role within the healthcare system. They can offer some services to the patients including consultation, patient education and therapeutic management. Community pharmacists can assess the type and severity of pain, monitor treatment and guide medication regulation to improve the treatment of the pain. The involvement of pharmacists in nonprescription medication counseling about pain will increase the public’s ability to understand the risks and benefits of over-the-counter drugs. Aim and objects was to study and analyze professional abilities and role of pharmacy employees during the pain management. The survey was conducted among 285 employees of licensed pharmacies in Armenia with the help of questionnaires, the number of which was determined according to “The Survey System Version 11.0”. Survey data were entered and analyzed using SPSS software package. The study was quantitative investigation and the questionnaire was developed based on the World Health Organization standard questionnaire. As a result of our research, it became clear that pharmacists have pure, indistinct knowledge about adverse reactions of over-the-counter analgesics and pharmacy employees in the Republic of Armenia have incomplete knowledge and ideas about pain management. According to the study pharmacists’ information sources was not reliable and the use of these sources in professional pharmaceutical practice were not inappropriate. Involvement of pharmacists in primary care pain management is very important and pain management training of pharmacy staffs should be encouraged. Pharmacist should be a part of a multidisciplinary pain management team and for this reason comprehensive information on pain management as well as development of practical skills should be included in continuing education programs for pharmacists.

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Consumer Healthcare Products Association response to Major et al., “Trends in rates of acetaminophen‐related adverse events in the United States”, Pharmacoepidemiology & Drug Safety, May 2016, 25: 590–8

Cited by 2 publications

References 1 publication

Five‐year trends in acetaminophen use exceeding the recommended daily maximum dose

Five‐year trends in acetaminophen use exceeding the recommended daily maximum dose

Evaluation of pharmacist interventions as part of a multidisciplinary pain management team

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