Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects

Abstract

The aqueous HSE investigated in this study enhanced the systemic AOP and reduced the oxidative stress in humans. Furthermore, the increased urinary hippuric acid excretion after HSE consumption indicates a high biotransformation of the ingested HSE polyphenols, most likely caused by the colonic microbiota.

Plant-Derived Polyphenols in Human Health: Biological Activity, Metabolites and Putative Molecular Targets

“…In a human intervention study, a systemic antioxidant potential was evaluated in eight healthy volunteers 24 h after the ingestion of 10 g of an aqueous HS extract. A significant increase in plasma and urine antioxidant potential and a reduction in oxidative stress was observed, in agreement with animal studies [49]. Furthermore, the main hibiscus anthocyanins and one glucuronide conjugate were detected in the urine of volunteers.…”

A pilot randomised controlled trial investigating a Mediterranean diet intervention in pregnant women for the primary prevention of allergic diseases in infants

“…Despite evidence of a correlation between the intake of foods with a high antioxidant content [e.g. walnuts , extract of Hibiscus sabdariffa and green tea ] and plasma and urinary FRAP having been demonstrated, we were not able to demonstrate using robust statistical analysis any differences between trial arms. This was most likely a result of the small sample size, and a ‘fade’ in compliance to the advice, as reflected in the smaller difference in the MD score between groups at 24 weeks compared to 12 weeks.…”

Comparative Studies on Bioactive Constituents in Hawk Tea Infusions with Different Maturity Degree and Their Antioxidant Activities

“…Ferric reducing activity power (FRAP) was evaluated according to the previous report in [16] using FeSO 4 ·7H 2 O as the standard. The fresh FRAP reagent was prepared before using, which contains 25 mL acetate buffer (300 mmol/L, pH 3.6), 2.5 mL TPTZ solutions (10 mmol/L in 40 mmol/L HCl), and 2.5 mL of FeCl 3 · 6H 2 O solution (20 mmol/L).…”