Consumption of Very Low Mineral Water Is Associated with Lower Bone Mineral Content in Children

Huang, Yujing; Ma, Xiangyu; Tan, Yao; Wang, Lingqiao; Wang, Jia; Lan, Lan; Qiu, Zhiqun; Luo, Jiaohua; Zeng, Hui; Shu, Weiqun

doi:10.1093/jn/nxz161

Cited by 26 publications

(34 citation statements)

References 24 publications

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“…That is not to deny the negative effect of heating food processing (Razzaque 2018;Workinger et al 2018;Nielsen 2019). Modern methods of softening and purifying water significantly reduce the magnesium content in drinking water (Huang et al 2019;Noy et al 2020). An unfavourable ecological situation with plenty of toxins and heavy metals in water, soil, air and food results in these substances displacing magnesium from the body (Karkashadze et al 2014;Lopresti 2020).…”

Section: Resultsmentioning

confidence: 99%

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

Sankova

Kytko

Meylanova

et al. 2020

RRP

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Introduction: The relevance of the issue of increasing stress resistance is due to a significant deterioration in the mental health of the population caused by the special conditions of the disease control and prevention during the COVID-19 pandemic. Recently, the decisive role in the severity of clinico-physiological manifestations of maladjustment to stress is assigned to magnesium ions. The aim of the work was to study the magnesium importance in the body coping mechanisms under stress for the pathogenetic substantiation of the magnesium correction in an unfavorable situation of disease control and prevention during the COVID-19 pandemic. Materials and methods: The theoretical basis of this scientific and analytical review was an analysis of modern Russian and foreign literature data posted on the electronic portals MEDLINE, PubMed-NCBI, Scientific Electronic Library eLIBRARY.RU, Google Academy, and CyberLeninka. Results and discussion: It was shown that the total magnesium level in the body plays the indicator role of the body functional reserves. Acute and chronic stresses significantly increase the magnesium consumption and cause a decrease in its body content. Magnesium deficiency is one of the main pathogenetic mechanisms of reducing stress resistance and adaptive body reserves. Arising during the COVID-19 pandemic, increased nervous and emotional tension, the lack of emotional comfort and balance can lead to the onset or deterioration of magnesium deficiency, which manifests itself in mental burnout and depletion of adaptive capacities. The inability to synthesize magnesium in the body necessitates including foodstuffs high in magnesium in the population diet during this period. The appointment of magnesium preparations is pathogenetically justified with moderate and severe magnesium deficiency. This therapy should take into account the major concomitant diseases, severity of magnesium deficiency, and a patient’s age. Conclusion: magnesium correction, carried out during the COVID-19 pandemic, will contribute to increasing stress resistance, preventing mental diseases and improving the population’s life quality.

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Section: Resultsmentioning

confidence: 99%

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

Sankova

Kytko

Meylanova

et al. 2020

RRP

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“…We did not observe alterations in bone microstructure in different drinking water groups before metabolic acidosis, and our previous study suggested that drinking low mineral water impairs bone quality in multi-generation ( 19 ). Considering that the consumption of water has been relatively fixed in people for years ( 11 , 13 , 15 ), we speculate that the impact of drinking water on bones takes a much longer time. Thus, the alterations in bone microstructural parameters are more like acute acid load by drinking water.…”

Section: Discussionmentioning

confidence: 97%

“…Endogenous and exogenous acids stimulate bone resorption to release calcium and other alkalis into the blood to maintain the body's acid-base balance ( 5 – 10 ). This procedure often disturbs the calcium regulating system, and induces excessive bone resorption and blood calcium increasing, resulting in destroying bone microstructure, reducing bone minerals, and weakening bone biomechanical properties ( 5 , 9 – 11 ).…”

Section: Introductionmentioning

confidence: 99%

Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis

Tan

Qiu

et al. 2022

Front. Nutr.

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IntroductionMetabolic acidosis affects bone health. It remains unclear whether drinking natural mineral water is better for maintaining bone health in the youth with metabolic acidosis.Materials and MethodsSixty young female rats (3-weeks-old) were randomly divided into three groups and drank purified water (PW, as control), bicarbonate-rich natural mineral water (Bic-NMW), or sulfate-rich natural mineral water (Sul-NMW), which, respectively, contained calcium (0.17, 155, and 175 mg/L), bicarbonate (0.1360, and 139 mg/L) and sulfate (0, 35.6, and 532 mg/L), for 16 weeks. In the last 3 weeks, metabolic acidosis was induced in 10 rats per group by adding NH4Cl (0.28 mM) to drinking water. The rats' blood, urine, and femur were collected for assessing acid-base status, calcium metabolism, bone microstructure, and strength. The difference between the three groups was determined using one-way ANOVA followed by the Student–Newman–Keuls test or Dunnett's T3 test.ResultsCompared with the PW rats, the Bic-NMW rats and the Sul-NMW rats had less urine net acid excretion (−1.51, 0.20 vs. 10.77, EQ/L), higher bone mineral density (442.50, 407.49 vs. 373.28, mg/mm3), growth cartilage width (271.83, 283.83 vs. 233.27, μm) and cortical trabecular area (9.33, 9.55 vs. 5.05, mm2), and smaller cortical marrow cavity area (5.40, 5.49 vs. 7.27, mm2) in the femur (P < 0.05). Besides, the Bic-NMW rats had less serum calcium (2.53 vs. 2.68, mmol/L) and C-terminal cross-linked telopeptide of type-I collagen (1.35 vs. 1.93, ng/mL), and higher serum calcitonin (0.61 vs. 0.39, μg/L), femoral trabecular thickness (0.10 vs. 0.09, μm), bone volume/total volume (0.42 vs. 0.34, %), cortical bone area (15.91 vs. 12.80, mm2), and ultimate stress (35.12 vs. 29.32, MPa) (P < 0.05). The Sul-NMW rats had more osteoclasts (22.50 vs. 11.54, cells/field) (P < 0.05).ConclusionsDrinking natural mineral water, especially bicarbonate-rich natural mineral water, is effective in improving bone health in young rats with metabolic acidosis. These benefits include maintaining bone mineral density, and improving bone microstructure and biomechanical properties via moderating metabolic acidosis.

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“…( 29) is the absolute value of the difference of the reference sequence (x0 * (k)) and comparable sequence (xi * (k)) distinguish coefficient ranging between 0 and 1, and it is generally used as 0.5 [24], [16], [25], [26], min and max are the lowest and the highest value of 0i, respectively. (28) (29) (30) (31) Based on GRC, GRG ( ) representing the level of the correlation between the reference sequence and comparability sequence is calculated by Eq. ( 32).…”

Section: Calculation Of Grey Relation Coefficients (Grc) Of the Norma...mentioning

confidence: 99%

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2023

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This study investigates the spatial and temporal changes in groundwater levels and quality in the Palas Basin, a relatively-pristine semi-arid agricultural basin in T . Although groundwater is solely used as irrigation and drinkingpotable water resource throughout the basin, measurements regarding the dynamics and quality of groundwater were quite rare. The analyses were based on data collected from 12 water quality monitoring wells and 15 groundwater level monitoring wells during June 2019-May 2020. Water samples were analyzed for pH, electrical conductivity, temperature, nitrate, nitrite, ammonium, total nitrogen, total hardness, alkalinity, chloride, sulfate, phosphate, total organic carbon, calcium, magnesium, sodium, potassium, and arsenic. Data analyses included hydrogeochemical analysis and multivariate statistical analysis such as principal component analysis and cluster analyses. Results showed that water quality in the basin is mostly controlled by natural factors, however, anthropogenic impacts from agriculture activities were apparent in some regions. The basin shows significant changes in water levels throughout the year due to irrigation activities. The groundwater quality was classified as either Ca-Mg-HCO3 and Ca-Mg-SO4 type. In the majority of the basin, water quality was suitable for irrigation and drinking water uses, however, a few sampling sites had very high electrical conductivity, sulfate, nitrate, and arsenic levels. The high levels of nitrates were detected in areas, where agriculture is intense, indicating that agricultural activities might be affecting water quality. High sulfate, electrical conductivity, and arsenic levels could be related to the hydrogeological setting of the basin. This study showed that agricultural activities and natural factors were effective on the hydrogeochemical characteristics of the Palas Basin.

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Consumption of Very Low Mineral Water Is Associated with Lower Bone Mineral Content in Children

Cited by 26 publications

References 24 publications

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

Possible prospects for using modern magnesium preparations for increasing stress resistance during COVID-19 pandemic

Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis

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