Contact Allergy in Children

Goossens, An; Morren, Marie‐Anne

doi:10.1007/978-3-319-72451-5_48-1

Cited by 3 publications

(2 citation statements)

References 148 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…• Furthermore, Type IV allergens (with very few exceptions) do not cause anaphylaxis, and systemic adverse events during patch testing procedures are extremely rare and almost never serious. The safety of the procedure is backed by many scientific papers, which, for example, focus on patch testing in (very young) children 20 or patch testing in severe cutaneous drug eruption. 21 The experience with patch testing is large enough to affirm that with the current practical guidelines and recommendations of scientific societies safety of patients is ensured.…”

Section: Impact Of Type IV Allergy and The Importance Of Obtaining A ...mentioning

confidence: 99%

“…Exposure to Type IV allergens from numerous consumer products in real life usually represents a more significant exposure and may cumulatively entail a much greater risk than their application for 2 days in small amounts during patch testing. Furthermore, Type IV allergens (with very few exceptions) do not cause anaphylaxis, and systemic adverse events during patch testing procedures are extremely rare and almost never serious. The safety of the procedure is backed by many scientific papers, which, for example, focus on patch testing in (very young) children 20 or patch testing in severe cutaneous drug eruption 21 …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Severely compromised supply of patch test allergens in Europe hampers adequate diagnosis of occupational and non‐occupational contact allergy. A European Society of Contact Dermatitis (ESCD), European Academy of Allergy and Clinical Immunology (EAACI), European Academy of Dermatology and Venereology (EADV) task forces ‘Contact Dermatitis’ and ‘Occupational Skin Disease’ position paper

John,

Bonertz,

Zimmer

et al. 2024

Contact Dermatitis

View full text Add to dashboard Cite

Patch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of Type IV patch test (PT) allergens in Europe, however, is currently scarce. This severely compromises adequate diagnostics of contact allergy, leading to serious consequences for the affected patients. Against this background, the European Society of Contact Dermatitis (ESCD) has created a task force (TF) (i) to explore the current availability of PT substances in different member states, (ii) to highlight some of the unique characteristics of Type IV vs. other allergens and (iii) to suggest ways forward to promote and ensure availability of high‐quality patch testing substances for the diagnosis of Type IV allergies throughout Europe. The suggestions of the TF on how to improve the availability of PT allergens are supported by the ESCD, the European Academy of Allergy and Clinical Immunology, and the European Academy of Dermatology and Venereology and intend to provide potential means to resolve the present medical crisis.

show abstract

Section: Impact Of Type IV Allergy and The Importance Of Obtaining A ...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Severely compromised supply of patch test allergens in Europe hampers adequate diagnosis of occupational and non‐occupational contact allergy. A European Society of Contact Dermatitis (ESCD), European Academy of Allergy and Clinical Immunology (EAACI), European Academy of Dermatology and Venereology (EADV) task forces ‘Contact Dermatitis’ and ‘Occupational Skin Disease’ position paper

John,

Bonertz,

Zimmer

et al. 2024

Contact Dermatitis

View full text Add to dashboard Cite

show abstract

Contact allergy in a paediatric population observed in a tertiary referral centre in Belgium

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background: Contact allergy is increasingly recognized as being important in children with eczema.Objectives: To retrospectively analyse the patch test results in children over the past 10 years, aiming to (1) evaluate demographic characteristics and lesion locations,(2) describe frequencies of positive patch test reactions, and (3) investigate the relationship with atopic dermatitis (AD).Methods: A total of 329 children were patch tested between January 2010 and December 2019 with the European (children) baseline series and/or other series, and the personal product(s) used.Results: A total of 119 (36%) children presented with at least one positive reaction.Children with AD had a higher prevalence of positive reactions compared with the non-AD group (P = .002), but without statistically significant difference regarding sensitization to more than one hapten (P = .39). The face (20.2%), hands (19.3%), feet (16.8%), arms (12.6%), and body folds (10.9%) were the most common sites of primary localizations. The most frequent contact allergens were nickel sulfate and linalool hydroperoxide (both 16%), limonene hydroperoxide (13.5%), and para-phenylenediamine (10.9%). No statistically significant difference for nickel sulfate was found between the AD and non-AD group (P = .20).Conclusions: Contact allergy in children with eczema was frequently observed in our tertiary referral centre in Belgium as well, confirming the need for patch testing.

show abstract

Contact allergy in children with and without atopic dermatitis: An Italian multicentre study

et al. 2022

View full text Add to dashboard Cite

Background Contact allergy and atopic dermatitis (AD) are both common inflammatory T cell‐mediated diseases and many factors may influence the prevalence of contact allergy in AD patients. In children, their possible correlation was debated with conflicting results. Objectives The present study aimed to assess the prevalence of contact sensitivity in children and to investigate the association with AD. Materials and methods A retrospective multicentre study on children aged from 0 to 14 years patch tested between January 2017 and December 2018 was performed. Children were consecutively patch tested with the SIDAPA (Società Italiana Dermatologia Allergologica Professionale Ambientale) baseline series. Results Among the 432 children investigated for contact allergy, 125 (28.9%) showed a positive reaction to at least one of the allergens tested, with a higher prevalence of positive patch test reactions in girls (32.3%) than in boys (25.0%). The most frequent contact allergens were nickel sulphate (10.2%), cobalt chloride (6.7%), methylisothiazolinone (3.7%), fragrance mix‐2 (3.2%), potassium dichromate (2.8%), fragrance mix‐1 (2.1%) and methylchloroisothiazolinone/methylisothiazolinone (2.1%). One‐hundred‐three children (23.8%) suffered from AD showing a higher prevalence of positive patch test (36.9%) compared to children without AD (26.4%). Conclusions Despite the topic being still controversial, the present study suggests a consistent prevalence of contact allergy among children with higher sensitivity rate among children with AD than without AD.

show abstract

Contact Allergy in Children

Cited by 3 publications

References 148 publications

Contact allergy in a paediatric population observed in a tertiary referral centre in Belgium

Contact allergy in children with and without atopic dermatitis: An Italian multicentre study

Contact Info

Product

Resources

About