Contact Allergy to Corticosteroids in Patients Using Inhaled or Intranasal Corticosteroids for Allergic Rhinitis or Asthma

Immediate and delayed allergic hypersensitivity to corticosteroids: practical guidelines

“…The frequency of CS allergy following topical application ranges from 0.2% to 5% of all patients attending patch test clinics (4). Despite the wide use of inhaled CSs, very few cases of asthmatic patients experiencing allergic reactions have been reported (5–7).…”

Steroid allergy in patients with inflammatory bowel disease

“…Allergy to steroids in nasal sprays and inhalers is well documented; 2 however, there has been only one reported case of allergic contact dermatitis from a steroid enema, as far as we are aware. Monk and Skipper 3 reported a 57‐year‐old patient who developed irritation from a steroid enema and tested positive to budesonide on patch testing.…”

“…1 Contact allergy to steroids in nasal sprays and inhalers has also been reported. 2 Corticosteroid enemas play an important role in the management of inflammatory bowel disease (IBD) affecting distal colon and rectum. Following the recent report of a case of allergic contact dermatitis to a corticosteroid enema 3 we decided to assess patients with IBD attending our gastroenterology clinics for evidence of allergic contact dermatitis to corticosteroids.…”

“…Delayed‐type hypersensitivity to topical corticosteroids manifesting as contact dermatitis is well documented 1 . Contact allergy to steroids in nasal sprays and inhalers has also been reported 2 . Corticosteroid enemas play an important role in the management of inflammatory bowel disease (IBD) affecting distal colon and rectum.…”

A contact allergic reaction to budesonide mimicking immediate‐type allergy

“…In contrast, corticosteroids only rarely cause immediate‐type allergic reactions . If contact allergy to inhaled corticosteroids is suspected, it is important to remember that patients are also exposed to common additives such as propylene glycol and benzalkonium chloride, and testing should therefore include these substances .…”