Contact Allergy to Resorcinol Monobenzoate

Ongenae, Katia; Matthieu, L.; Constandt, L.; Hecke, Eric Van

doi:10.1159/000017953

Cited by 11 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The second patient was most probably sensitized by resorcinol monobenzoate, an ultraviolet light absorber used in cellulose plastics and that is known to cause allergic contact dermatitis (5). Hearing aids have only occasionally been mentioned as a source of exposure and sensitization, although spectacle frames seem to be more frequently involved (6). Resorcinol probably cross-reacts with resorcinol monobenzoate, which is most probably transformed into resorcinol in the skin, thus acting as a prohapten.…”

Section: Discussionmentioning

confidence: 99%

Resorcinol: a strong sensitizer but a rare contact allergen in the clinic

Darcis

Goossens

2016

Contact Dermatitis

View full text Add to dashboard Cite

Resorcinol is a simple aromatic chemical (1,3benzenediol) that has widespread use as a coupler in hair dyes and food, for example as an anti-browning agent in crustaceans (1), and, because of its antipruriginous, keratolytic and antifungal properties, in topical pharmaceutical products, such as Castellani paint. Moreover, it is present in certain skin markers. According to the local lymph node assay in mice, resorcinol has an EC3 value of 5.5% (2), and was classified as a moderate sensitizer, whereas, according to the Scientific Committee on Consumer Safety, it has an EC3 value of 1.4%, and was classified as a strong sensitizer (1). Here, we report our experience with patch testing (January 1990 to November 2015) with resorcinol 1% in petrolatum (pet.) in 1187 selected subjects: (i) as a part of the hairdressers' series, (ii) when it had been used topically, or (iii) to check for cross-reactivity. Only 5 positive patch test reactions were observed, and these cases will be discussed here.

show abstract

Section: Discussionmentioning

confidence: 99%

Resorcinol: a strong sensitizer but a rare contact allergen in the clinic

Darcis

Goossens

2016

Contact Dermatitis

View full text Add to dashboard Cite

show abstract

“…Any plastic frame made before about 1975, which is still in reasonable condition, is likely to be made from cellulose acetate. There are few reported instances of allergy to cellulose acetate spectacle frames (50), but some reports of reactions to additives and polishes (51–53).…”

mentioning

confidence: 99%

“…However, it is not clear whether this applies to frames that are available outside the USA. Interestingly, Ongenae (51) in 1998 claimed that it was still the most important allergen in plastic spectacle frames. Phenyl salicylate is sometimes used as a UV inhibitor in cellulose plastics and has been reported as causing dermatitis in spectacle frames (55).…”

mentioning

confidence: 99%

Materials and allergens within spectacle frames: a review

Walsh¹,

Wilkinson²

2006

Contact Dermatitis

View full text Add to dashboard Cite

The materials that have been reported as causing allergic contact dermatitis within spectacle frames are identified, and their most likely location on the frame is highlighted. The lack of any real control over spectacle frame quality and content is indicated to be a problem, as is the difficulty in determining the true source of many frames. Much of the information must be obtained from anonymous sources in the industry, historical 'common knowledge' of indeterminate source or reports of dermatological problems.

show abstract

Allergic contact dermatitis caused by Solvent Orange 60 dye in the temple tips of eyeglasses and a review of cases of eyeglass allergic contact dermatitis

Nishihara¹,

Sasaki

2018

J Cutaneous Imm & Allergy

View full text Add to dashboard Cite

Background A 57‐year‐old Japanese woman developed eczematous skin lesions behind both ears 10 days after she began using a new pair of glasses. The skin lesions resolved two weeks after she stopped wearing the glasses. Methods Patch testing for material scraped from the temple tips of the glasses was performed. A +2 reaction to the scraped material was observed on D2 and D3. Chemical analyses were performed to determine the causative allergen. A second patch test was performed with 6 fractions from the temple tips and Solvent Orange 60. We retrieved literature addressing eyeglass allergic contact dermatitis from MEDLINE (1997‐2017). Results Patch tests and chemical analyses of the temple tips of the glasses revealed that Solvent Orange 60 dye was a causative allergen. Conclusions We report a case of contact dermatitis caused by Solvent Orange 60 dye in the temple tips of eyeglasses. Overall, causative allergens of eyeglass allergic contact dermatitis include metals, plastics, plasticizers, solvents, UV stabilizers, antioxidants, dyes, waxes and preservatives; metals and dyes have been the most common such allergens in recent years.

show abstract

Contact Allergy to Resorcinol Monobenzoate

Cited by 11 publications

References 11 publications

Resorcinol: a strong sensitizer but a rare contact allergen in the clinic

Resorcinol: a strong sensitizer but a rare contact allergen in the clinic

Materials and allergens within spectacle frames: a review

Allergic contact dermatitis caused by Solvent Orange 60 dye in the temple tips of eyeglasses and a review of cases of eyeglass allergic contact dermatitis

Contact Info

Product

Resources

About