Contact Angle Studies on Porous Silicon: Evidence for Heterogeneous Wetting and Implications of Oxidation

Spencer, Stephen J.; Deacon, Christopher G.; Andrews, G. Todd

doi:10.1007/s12633-023-02384-9

Silicon

2023

DOI: 10.1007/s12633-023-02384-9

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Contact Angle Studies on Porous Silicon: Evidence for Heterogeneous Wetting and Implications of Oxidation

Stephen J. Spencer

Christopher G. Deacon

G. Todd Andrews

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2024

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Cited by 2 publications

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Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties

Tromp,

van der Boon,

de Hilster

et al. 2024

Advanced Science

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Biomaterial‐associated fibrosis remains a significant challenge in medical implants. To optimize implant design, understanding the interplay between biomaterials and host cells during the foreign body response (FBR) is crucial. Material properties are known to influence cellular behavior and can be used to manipulate cell responses, but predicting the right combination for the desired outcomes is challenging. This study explores how combined physicochemical material properties impact early myofibroblast differentiation using the Biomaterial Advanced Cell Screening (BiomACS) technology, which assesses hundreds of combinations of surface topography, stiffness, and wettability in a single experiment. Normal human dermal fibroblasts (NHDFs) are screened for cell density, area, and myofibroblast markers α‐smooth muscle actin (α‐SMA) and Collagen type I (COL1) after 24 h and 7 days of culture, with or without transforming growth factor‐beta (TGF‐β). Results demonstrated that material properties influence fibroblast behavior after 7 days with TGF‐β stimulation, with wettability emerging as the predominant factor, followed by stiffness. The study identified regions with increased cell adhesion while minimizing myofibroblast differentiation, offering the potential for implant surface optimization to prevent fibrosis. This research provides a powerful tool for cell‐material studies and represents a critical step toward enhancing implant properties and reducing complications, ultimately improving patient outcomes.

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Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties

Tromp,

van der Boon,

de Hilster

et al. 2024

Advanced Science

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Смачиваемость Слоев Черного Кремния, Сформированных Различными Методами

Айвазян,

Варданян,

Семченко

2024

Proceedings of NAS RA. Physics

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Исследована смачиваемость слоев черного кремния (b-Si), сформированных методами реактивного ионного травления, металл-стимулированного химического травления и лазерно-индуцированного травления. Определены краевые углы смачивания изготовленных образцов деионизованной водой, глицерином, дийодметаном и этиленгликолом. Показано, что поверхностная пленка окисла кремния и коэффициент увеличения площади слоев b-Si оказывают существенное влияние на их смачиваемость, варьируя от гидрофильных к гидрофобным свойствам. Հետազոտվել է ռեակտիվ իոնային խածատման, մետաղով խթանմամբ քիմիական խածատման և լազերային խածատման մեթոդներով ձևավորված սև սիլիցիումի (b-Si) շերտերի թրջելիությունը: Գնահատվել են պատրաստված նմուշների դեիոնացված ջրով, գլիցերինով, դիյոդմեթանով և էթիլենգլիկոլով թրջման հպակային անկյունները: Ցույց է տրվել, որ սիլիցիումի օքսիդի մակերևութային թաղանթը և b-Si շերտերի մակերեսի մեծացման գործակիցը զգալի ազդեցություն ունեն թրջելիության վրա՝ ապահովելով հիդրոֆիլայինից մինչև հիդրոֆոբային հատկություններ: The wettability of black silicon (b-Si) layers formed by reactive ion etching, metal-assisted chemical etching, and laser-induced etching has been studied. The wetting contact angles of the prepared samples with deionized water, glycerol, diiodomethane and ethylene glycol were determined. It has been shown that the silicon oxide surface film and the enlargement area factor of b-Si layers have a significant effect on their wettability, varying from hydrophilic to hydrophobic properties.

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Contact Angle Studies on Porous Silicon: Evidence for Heterogeneous Wetting and Implications of Oxidation

Cited by 2 publications

References 37 publications

Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties

Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties

Смачиваемость Слоев Черного Кремния, Сформированных Различными Методами

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