Contact dermatitis as an adverse reaction to some topically used <scp>E</scp>uropean herbal medicinal products – part 1: <i>Achillea millefolium–Curcuma longa</i>

Calapai, Gioacchino; Miroddi, Marco; Minciullo, Paola Lucia; Caputi, Achille P.; Gangemi, Sebastiano; Schmidt, Richard J.

doi:10.1111/cod.12222

Cited by 37 publications

(24 citation statements)

References 86 publications

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“…Though a combination of neem and turmeric powder was effective in human scabies, in vitro studies and further human studies are needed . Turmeric can stain skin and may cause contact urticaria and allergic contact dermatitis …”

Section: Essential Oils and Plant Extractsmentioning

confidence: 99%

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Tackling scabies: novel agents for a neglected disease

2018

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The scabies mite, Sarcoptes scabiei var hominis, is an obligate ectoparasite of humans. It has been a source of distress for humanity since antiquity. The troublesome mite is emerging triumphant over current acaricidal agents with reports of emerging resistance and treatment failures. Scabies in endemic areas and crusted scabies offer additional management challenges. Exploration of indigenous plants and better understanding of mite biology and pathogenesis provide opportunities for the development of novel agents for this common pest. We review the recent diverse approaches to scabies, including the use of novel plant products with a better safety profile, translating the use of moxidectin from veterinary practice to human scabies, vaccination, immunotherapy, and development of drugs that directly target mite molecules.

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Section: Essential Oils and Plant Extractsmentioning

confidence: 99%

“…7 Turmeric can stain skin and may cause contact urticaria and allergic contact dermatitis. 35,36 Camphor oil Camphor oil is extracted from Eucalyptus globulus. Camphor oil is effective with or without glycerol against zoonotic scabies.…”

Section: Turmeric (Curcuma Longa)mentioning

confidence: 99%

Tackling scabies: novel agents for a neglected disease

2018

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“…It has also anti-inflammatory effects when used topically (Lemmens-Gruber et al, 2006;Zhang et al, 2014). Furthermore, the species Achillea millefolium could be beneficial in preventing and/ or treating neurodegenerative diseases like Alzheimer and Parkinson (Elmann et al, 2011) as well as in 65 cosmetic formulations (Schmidt et al, 2014) while Achillea eriophora and Achillea biebersteinii have shown to induce protective properties against oxidation, cytotoxicity and DNA dam-age (Varasteh-Kojourian et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Ameliorating Effect of Achillea fragrantissima Against Benzene-Induced Skin Irritation: Histological Study

Al-Shathly¹,

Alqahtani²

2017

Adv. Pharm. Ethnomed

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| Organic solvents such as car fuel, which contains benzene and other solvents were known to cause skin irritation and contact dermatitis. Although anti-inflammatory steroids topical medications were used, they may result in side effects in susceptible persons. Herbal preparation was tried in literature. In the present study, Achillea fragrantissima, a wild plant in some areas of Saudi Arabia was used to speed slow-healing wounds. Thus, the study was designed to investigate its efficacy to treat experimentally induced benzene-dermatitis in mice skin. Twenty-five adult mice were shaved and animals were divided into GI as control and GII as benzene painted. The later was further divided into four subgroups; untreated, steroidal medicinal cream treated, a group treated with olive oil extract of Achillea (dried plant soaked in olive oil) and a group treated with olive oil only. Gross and histopathological observation were used to evaluate the treatment effects. Benzene painting produced skin hardening, scaling, epidermal hyperplasia and inflammatory reaction in skin dermis. Decrease in the hypodermal adipose tissue thickness was observed, those pathological changes were much improved or even absent in treated mice. Such results are similar to that observed in the group treated by medicinal cream. Achillea plant could be a source of future effective anti-dermatitis cream medicinal formulation against benzene-induced dermatitis. Olive oil extract of Achillea will be tested and compared to olive oil alone to prove the hypothesis.

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“…Many topical plant products used in traditional Chinese medicine are known to cause contact dermatitis . Here, we report a case with contact dermatitis caused by Caesalpinia sappan .…”

mentioning

confidence: 96%

Contact dermatitis caused by brazilin in Caesalpinia sappan

Yin

2015

Contact Dermatitis

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Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 1: Achillea millefolium–Curcuma longa

Cited by 37 publications

References 86 publications

Tackling scabies: novel agents for a neglected disease

Tackling scabies: novel agents for a neglected disease

Ameliorating Effect of Achillea fragrantissima Against Benzene-Induced Skin Irritation: Histological Study

Contact dermatitis caused by brazilin in Caesalpinia sappan

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