Contact Dermatitis Owing to Tincture of Benzoin

Coskey, Ralph J.

doi:10.1001/archderm.1978.01640130086037

Cited by 15 publications

(6 citation statements)

References 3 publications

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“…2,3 It has been used added to water and glycerine in preparing steam inhalations for bronchitis, asthma and other respiratory disorders. [1][2][3]6,10,11,13 There have been few reports of contact allergy to CTB, and none in the last decade, suggesting that CTB is in fact not a strong sensitizer. 10,11 Compound tincture of benzoin is usually applied under occlusion, and often on injured skin, in a warm, moist environment for a prolonged period of time.…”

Section: Discussionmentioning

confidence: 99%

“…Another reason could be that CTB is called other names such as Friars' balsam or trade names such as 'Cold Sore Lotion'®, 'Nappy-Mate'®, 'Nyal Cold-Sore'®, to name a few such examples. 6 Some surgeons routinely use CTB prior to applying dressings to wounds to -++ -++ 7. 6,11,13 It has been suggested that anyone with CTB allergy should be asked about previous adhesive tape allergy as CTB is often used to enhance the adhesiveness of dressings, including Elastoplast® and other 'sticky' dressings.…”

Section: 4 Benzoin Itself Contains Not Onlymentioning

confidence: 99%

“…3 Styrax tonkinensis is the source of Siam benzoin. 6 Compound tincture of benzoin can also contain myrrh and angelica, and occasionally balsam of Peru. Sumatra benzoin is less allergenic and is the form used for inhalations.…”

Section: Introductionmentioning

confidence: 99%

“…Sumatra benzoin is less allergenic and is the form used for inhalations. 6 The first case of benzoin allergy was reported in 1874, in a patient who developed a purpuric eruption after inhaling a vapour containing CTB. 4,5 The composition in various pharmaceutical preparations is the same, whether Siam or Sumatra benzoin is used.…”

Section: Introductionmentioning

confidence: 99%

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Compound tincture of benzoin: A common contact allergen?

Scardamaglia

Nixon

Fewings³

2003

Aust J Dermatology

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The results of patch testing to compound tincture of benzoin in 477 patients performed at the Contact Dermatitis Clinic at the Skin and Cancer Foundation in Melbourne during 1999 are presented. There have been fewer than 30 reported cases of contact allergy from compound tincture of benzoin, and none in the last decade. Our results showed 45 out of the 477 patients had a positive reaction to compound tincture of benzoin, which was the third most common allergen in our series. Of these 45 patients, 14 had strong positive reactions, but only two definitely recalled exposure to compound tincture of benzoin and these were clinically relevant. Twenty-eight of these patients had cross-reactions to similar allergens (fragrance mix, balsam of Peru, colophony and tea tree oil). Of the 14 patients with a strong positive reaction to compound tincture of benzoin, 11 had at least one other positive cross-reaction to the above allergens. This may explain the high frequency of reaction to compound tincture of benzoin found in our study.

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Section: Discussionmentioning

confidence: 99%

Section: 4 Benzoin Itself Contains Not Onlymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Compound tincture of benzoin: A common contact allergen?

Scardamaglia

Nixon

Fewings³

2003

Aust J Dermatology

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“…26,33,34 There is no evidence that these reactions have any bearing on skin problems reported in the DD area.…”

Section: Resultsmentioning

confidence: 99%

HETA 96-0266-2702, Cooper Engineered Products, Bowling Green, Ohio.

1998

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Severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray in an anesthesiologist

2009

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We describe the clinical presentation and management of an anesthesiologist who developed a severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray. A previously healthy male anesthesiologist with a small laceration between his right thumb and forefinger used a tincture of benzoin aerosol spray to improve adhesion of a small bandage immediately before performing a spinal anesthetic. He had previously used benzoin for skin reinforcement on several occasions during weight-lifting. The anesthesiologist experienced severe pruritus in the affected hand 48 h after benzoin exposure. A well-demarcated, bright red erythematous confluent vesicular dermatitis with and without painful hemorrhagic bullae erupted on the palmar and dorsal surfaces, respectively, of his hand, accompanied by pronounced edema. The palmar bullae were drained with several small incisions and the anesthesiologist was treated with intravenous methylprednisolone. He was unable to work for 10 days while the dermatitis gradually resolved. The case emphasizes that occupational exposure to benzoin represents a potential risk for operating room personnel who may be susceptible to cutaneous delayed hypersensitivity-mediated allergic reactions as a result of previous exposure to benzoin or chemically related cross-reacting substances.

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Contact Dermatitis Owing to Tincture of Benzoin

Cited by 15 publications

References 3 publications

Compound tincture of benzoin: A common contact allergen?

Compound tincture of benzoin: A common contact allergen?

HETA 96-0266-2702, Cooper Engineered Products, Bowling Green, Ohio.

Severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray in an anesthesiologist

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