Contact dermatitis to Kathon CG

Tosti, Antonella; Manuzzi, P.; Padova, Maria Pia De

doi:10.1111/j.1600-0536.1986.tb05298.x

Cited by 15 publications

(5 citation statements)

References 3 publications

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“…Twenty studies with a total of 175 patients (age range, 13–72 years) were found describing scalp ACD secondary to prescription treatment for inflammation or hair regrowth 4,6,8,9,11,13,77–90 . The most commonly reported patch test–proven scalp ACD agent was 1%, 2%, 4%, or 5% minoxidil topical solution, foam, or lotion (n = 19).…”

Section: Resultsmentioning

confidence: 99%

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

et al. 2022

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Hair products are commonly used to maintain hair health or cosmesis. Products applied to the scalp and hair contain multiple active and inactive ingredients that can potentially cause irritant and/or allergic contact dermatitis. The objectives of this study were to identify and to discuss the most common allergens in scalp and hair applied products causing scalp allergic contact dermatitis (ACD). A PubMed search identified 99 studies, with 3185 patients and 31 categories of scalp products. Hair products reportedly associated with scalp ACD were hair dyes (41%), shampoos (28%), and conditioners (22%). The most commonly reported patch test–positive allergens were p-phenylenediamine (23%), nickel (15%), fragrance mix (13%), balsam of Peru (10%), cocamidopropyl betaine/3-dimethylaminopropylamine (7%), and methylchloroisothiazolinone/methylisothiazolinone (6%). Common symptoms and signs include eczematous lesions, pruritus, and a burning sensation. Medical practitioners should be aware of causative agents to provide appropriate patient education, counseling, and/or treatment.

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Section: Resultsmentioning

confidence: 99%

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

et al. 2022

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“…De Groot reported an increasing frequency of sensitization to ( chloro )isothiazolinone (from 1.4% in 1985 to 5% in 1986--87) in the Netherlands (19)(20)(21). Certain other groups in Italy have also found an upward trend (22,23). At present, the use of (chloro)isothiazolinone in drugs, foods and dermatological products is not approved by the EC (European Community) (14).…”

Section: Discussionmentioning

confidence: 99%

Results of routine patch testing of 834 patients in Turin

Castiglioni¹,

Carosso²,

Manzoni³

et al. 1992

Contact Dermatitis

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834 consecutive patients (630 female), aged between 26 and 46 years, who were suspected of having allergic contact dermatitis were patch tested with the GIRDCA standard series during 1989-1990. The most frequent sensitizers observed included nickel sulphate, cobalt, Kathon CG, perfumes, potassium dichromate and balsam of Peru. We have evaluated the influence of individual factors such as sex, age and occupation on the patch test results, and the coexistence of 2 or more unrelated but statistically significant sensitivities.

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“…The previOusly reported mctdences of Kathon CG sensitivity m larger senes have vaned s1g- (6) Denmark 1986 1511 13 0.86 PUT(+) 0/11 (7) Hungary 1986 300 0 0.00 "safe" brocide (5) Italy 1986 98 6…”

Section: Discussionmentioning

confidence: 99%

“…6.12 used at 0.01% m H20 own cosmetics negative (4) West Germany nificantly according to the nature of the product exposure, the concentratiOn of the agent, the patient populatiOn, and the geographic lo-catiOn (Table 3) (1-9). High InCidences of sen-SitiVIty were found m the Scandinavian countnes (particularly Finland [1] and Sweden [3]), the Netherlands (2), West Germany (4), and Italy (5). In these areas, the prevalence of contact sensit!Vlty to Kathon CG m contact dermatitis climes ranged from 3.35% to 8.70%, an mcrease m the Incidence of sensitiVIty as more mdividuals are exposed for longer perwds of time IS an additional trend noted (1,8 Both wash-off and leave-on cosmetic formu-latiOns contammg Kathon CG may act as sen-sitizatiOn sources, With the latter presumed to have greater sensitlzmg capability; concen-tratiOns of 5 to 19 ppm are common.…”

Section: Discussionmentioning

confidence: 99%

Sensitivity to Kathon CG: findings in 365 consecutive patients

Fransway

1988

Contact Dermatitis

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In the period from 1983 through 1986, 365 consecutive patients suspected as having allergic contact dermatitis were tested for reaction to Kathon CG. This test was positive in 20 of these patients: irritant responses in 7 and allergic sensitivity in 13. Provocative use testing was positive in 1 of the 3 allergic patients tested. The characteristics of this group of patients include having a mean age older than that of the general population or of our population of dermatologic patients, having histories of long-standing dermatitis, and reporting exposure to various leave-on formulations. Our rate of positive tests, 3.6%, is similar to that reported by other investigators, although sensitivity testing results differ from center to center. It is recommended that, in certain clinical situations, caution be exercised in the unsupervised use of leave-on products containing Kathon CG.

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Contact dermatitis to Kathon CG

Cited by 15 publications

References 3 publications

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

Results of routine patch testing of 834 patients in Turin

Sensitivity to Kathon CG: findings in 365 consecutive patients

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