Contact dermatitis to triclosan

Veronesi, S.; Padova, De; Vanni, Daniele; Melino, M.

doi:10.1111/j.1600-0536.1986.tb01359.x

Cited by 19 publications

(8 citation statements)

References 3 publications

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“…Contact sensitivity to trichlosan was first reported in 1975, from deodorant foot powder and a deodorant stick (3). Since then, there have been several case reports of contact sensitization from an antiperspirant spray (4), a steroid‐antibiotic combination cream (Logamel – no longer available) (5) and antibacterial hand washes (6) This is as far as we are aware, the first reported case of trichlosan contact sensitivity from toothpaste. Our patient was commenced on trichlosan‐free toothpaste and has had no further problems.…”

mentioning

confidence: 85%

Contact dermatitis to triclosan in toothpaste

Robertshaw

Leppard²

2007

Contact Dermatitis

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mentioning

confidence: 85%

Contact dermatitis to triclosan in toothpaste

Robertshaw

Leppard²

2007

Contact Dermatitis

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“…Although occasionally photosensitization has been described, the widespread use of triclosan in deodorants and soaps apparently indicates an exceedingly low potential for sensitization [Roed-Petersen et al, 1975;Lachapelle and Tennstedt, 1979;Hindson, 1975;Wahlberg, 1976;Veronesi et al, 1986;Steinkjer and Braathen, 1988;Wong and Beck, 2001;Gloor et al, 2002]. However, 10 from 88 patients with (photo)allergies to UV filters in suncreams reacted to triclosan [Schauder, 2001].…”

Section: Sensitization and Photosensitizationmentioning

confidence: 99%

Hygienic Relevance and Risk Assessment of Antimicrobial-Impregnated Textiles

Krämer¹,

Heldt³

et al. 2006

Current Problems in Dermatology

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The antimicrobial impregnation of textiles is intended to provide protection of textiles against microbial corrosion, prevention of malodor or prophylaxis and therapy of infections, respectively. For every biocidal product a careful risk assessment for humans and the environment has to be performed. The advantage of antimicrobially active textiles has to be documented for every agent as well as for every application, and a balance has to be found between a textile's quality rating and the potential risks, e.g. sensitization, disturbance of the ecology of the skin, toxic side effects by means of systemic absorption, cytotoxicity, genotoxicity, carcinogenicity, teratogenicity and ecotoxicity. This article evaluates the applicability of silver compounds as well as the classic antimicrobials triclosan, quaternary ammonium compounds, copper and further new options like chitosan and zeolite. It has to be emphasized that there are no objections against the use of antimicrobially active textiles if their use is equal or superior to other preventive or therapeutic measures. This applies to the amelioration of the course of dermatological diseases with disturbed skin flora, in particular atopic dermatitis, the prevention and therapy of acute and chronic wound infections by wound dressings, the use of impregnated surgical suture material as well as special indications in the prevention of infection in medical facilities. The use of antimicrobial textiles for the prevention of dermatomycosis by antifungal impregnation is of questionable use; the antimicrobial impregnation of textiles for deodorization purposes has to be avoided. Presently, from a hygienic point of view, the following questions have to be clearly determined: declaration of any antimicrobial impregnation; development of international standards for in vitro testing and preclinical evaluation of efficacy and tolerance; evaluation of the advantage of the antimicrobial properties for the intended use including the risk-benefit assessment.

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“…Triclosan hat keine irritative, fotoallergene, fototoxische, mutagene, teratogene oder kanzerogene Wirkung und nur eine geringe sensibilisierende Wirkung an der menschlichen Haut [4,5,6,19,20]. Eine systemtoxische und hepatotoxische Wirkung, die prinzipiell denkbar wären [21,22,23], dürften zumindest nach dem Säuglingsalter aufgrund der Literaturangaben über die toxisch wirksamen Dosen und die Wirkstoffresorption in Arealen ohne floride Ekzemherde oder Erosionen nicht möglich sein [3,5,19,20].…”

Section: In-vitro-untersuchungenunclassified

“…Eine systemtoxische und hepatotoxische Wirkung, die prinzipiell denkbar wären [21,22,23], dürften zumindest nach dem Säuglingsalter aufgrund der Literaturangaben über die toxisch wirksamen Dosen und die Wirkstoffresorption in Arealen ohne floride Ekzemherde oder Erosionen nicht möglich sein [3,5,19,20]. Gegen die Anwendung der geprüften Triclosancreme zur Rezidivprophylaxe nach Abheilung einer atopischen Dermatitis oder von Ulcera crurum bzw.…”

Section: In-vitro-untersuchungenunclassified