Contact hypersensitivity and allergic contact dermatitis among school children and teenagers with eczema

Czarnobilska, Ewa; Obtułowicz, Krystyna; Dyga, Wojciech; Wsolek-Wnek, Katarzyna; Śpiewak, Radosław

doi:10.1111/j.1600-0536.2009.01537.x

Cited by 55 publications

(53 citation statements)

References 25 publications

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“…However, the exact relationship between atopic dermatitis and allergic contact dermatitis is somewhat complex and controversial as the studies are conflicting (2,3). Our case series may support this notion, as a probable contact dermatitis to the car seat was observed in 12 ⁄ 21 atopic patients (57%), compared with 9 ⁄ 21 patients (43%) without an atopic background.…”

Section: Discussionsupporting

confidence: 74%

“Car Seat Dermatitis”: A Newly Described Form of Contact Dermatitis

Ghali¹

2011

Pediatric Dermatology

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Over the last several years, our clinic has documented an increasing trend of contact dermatitis presenting in areas that are in direct contact with certain types of car seats composed of a shiny, nylon-like material. Our practice has encountered these cases in both atopic and nonatopic infants, with a seasonal predilection for the warmer months. This brief report highlights some of the key features of this condition and alerts the clinician to this newly described form of contact dermatitis.

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Section: Discussionsupporting

confidence: 74%

“Car Seat Dermatitis”: A Newly Described Form of Contact Dermatitis

Ghali¹

2011

Pediatric Dermatology

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“…In the literature, most studies stated NS as being the most common contact allergen, at a frequency of 14.9%-59.1% in patients with positive patch test reactions (2)(3)5,7,17). Accordingly, in our study population, NS was the most common positive reaction with a frequency of 37.8% (17/45).…”

Section: Discussionmentioning

confidence: 84%

“…These may be taken into account as warning points for investigating children with AD for possible contact sensitization. In the literature, the frequency of contact sensitization of children with AD was reported as 6.2% to 89% in different countries worldwide (2)(3)(4)(5)(6)(7). This wide range of frequency may be due to the usage of different contact allergen panels and inclusion of different age groups of children in different studies.…”

Section: Discussionmentioning

confidence: 99%

The patterns and clinical relevance of contact allergen sensitization in a pediatric population with atopic dermatitis

Akan¹,

Toyran²,

Vezir³

et al. 2015

Turk J Med Sci

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Background/aim: Data about contact allergen sensitization (CAS) in children with atopic dermatitis (AD) are limited. The purpose of this study was to identify the frequency and patterns of CAS in children with AD by using a ready-to-use patch test system. Materials and methods:After receiving the history of CAS in the patients, the severity of AD and IgE-mediated allergen sensitization were determined.Results: Of 134 children with AD, 33.8% (n = 45) had at least 1 positive reaction. The most frequent positive reaction was to nickel sulfate (NS) (37.8%, 17/45), followed by methylchloroisothiazolinone (20.0%, 9/45) and thimerosal (15.6%, 7/45). The total Scoring Atopic Dermatitis (SCORAD) score was significantly higher in the NS-sensitized group (P = 0.036). The patients with NS sensitization had moderate-severe AD more frequently than those without any reaction (P = 0.020). When the SCORAD score was evaluated in detail, extent of eczema, score of sleep loss, and pruritus were significantly higher in the patients with NS sensitization than those without any reaction (P = 0.002, P = 0.001, and P = 0.002, respectively). Conclusion:Our study confirms the necessity of CAS in the management of AD. In particular, NS sensitization should be considered for children with severe AD or larger extent of eczema and trunk involvement.

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“…These data are in contrast with previously reported rates not only in the general population, 18 but also in older children. 5,14 However, very recent studies 19,20 have shown a higher prevalence of positive patch test reactions in younger male children.…”

Section: Discussionmentioning

confidence: 98%