Contact lens wear in pregnancy

Imafidon, Chris; Imafidon, Joe E.

doi:10.1016/s0141-7037(91)80045-n

Cited by 9 publications

(10 citation statements)

References 21 publications

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“…Corneal sensitivity can be reduced in pregnancy, and this in turn can increase susceptibility to serious corneal infections including post-laser surgery. 4 • Lens -a myopic shift in the lens results from increased lens curvature in pregnancy, resulting in a change in refraction. Furthermore, a temporary loss of accommodation can be seen in the immediate postpartum period.…”

Section: Physiological Ocular Changes In Pregnancymentioning

confidence: 99%

Ophthalmic associations in pregnancy

Qin¹,

Chen²,

Cugati³

2020

Aust J Gen Pract

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Background A range of ocular pathology exists during pregnancy. Some pre-existing eye conditions, such as diabetic retinopathy, can be exacerbated during pregnancy. Other conditions manifest for the first time during pregnancy as a result of complications such as pre-eclampsia and eclampsia. Early recognition and understanding of the management of ophthalmic conditions is crucial. Objective The aim of this article is to discuss the physiological and pathological changes in the eyes of pregnant women. Pathological changes are subdivided into: 1) pre-existing eye conditions modified during pregnancy, 2) pathological conditions occurring for the first time and 3) ophthalmic associations due to complications in pregnancy. Discussion This article reviews the ophthalmic conditions that can manifest during pregnancy and discusses their pathophysiology and clinical implications. Recognition, history and examination of ophthalmic conditions and a diagnostic framework for referral are provided. Fundamental multidisciplinary care principles involving the primary care physician, ophthalmologist, rheumatologist or haematologist and obstetrician in the care of the pregnant patient are discussed.

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Section: Physiological Ocular Changes In Pregnancymentioning

confidence: 99%

Ophthalmic associations in pregnancy

Qin¹,

Chen²,

Cugati³

2020

Aust J Gen Pract

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“…Corneal curvature also changes during pregnancy 4. Women taking contraceptives5 report problems with hard contact lenses and pregnant women frequently complain of contact lens intolerance 6. Currently, much interest is focused on research into the influence of oestrogen on the cornea in relation to corneal stability after corneal refractive surgery, as seen in studies concerning regression after photorefractive keratectomy (PRK) and after laser-assisted in situ keratomileusis (LASIK) 7.…”

mentioning

confidence: 99%

Oestrogen-induced changes in biomechanics in the cornea as a possible reason for keratectasia

Spoerl

Zubaty

Raiskup-Wolf

et al. 2007

British Journal of Ophthalmology

128

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Aim: The risk of regression after photorefractive keratectomy (PRK) and the tendency to develop keratectasia after laser-assisted in situ keratomileusis (LASIK) procedure is higher in women than men. Currently, interest is focused on the influence of oestrogen on corneal stability after corneal refractive surgery. The aim of this experimental study was to investigate the change in biomechanical properties of the cornea induced by oestrogen. Methods: The influence of oestrogen was investigated in 12 fresh porcine corneas incubated in culture medium with 10 mmol/l b-oestradiol for 7 days. A group of 12 porcine corneas incubated in culture medium without oestradiol for the same time served as a control group. Strips of cornea were cut and the stress-strain was measured in a biomaterial tester. The Young's modulus was calculated. Results: During incubation the thickness of the cornea changed in the control group by only 6.4% and in the oestradiol group by 12%. However, the difference in the biomechanical stress values at 10% strain was significantly larger. In the control group the stress value was 120.18¡28.93 kPa and in the oestradiol group 76.87¡34.63 kPa (p = 0.002), representing a reduction of the corneal stiffness by 36% due to the oestradiol treatment. Conclusion: Oestrogen is a modulating factor of the biomechanical properties of the cornea that is not explainable only by an increased swelling. The significance of the hormone status of patients and its influence on the biomechanical stability of the cornea, a determining factor after refractive surgery, have been underestimated and may contribute to the development of keratectasia.

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“…Several reasons may account for the increase in dry eye disease in pregnancy. Researchers have demonstrated that dry eye disease during pregnancy may be due to damage to the lacrimal acinar cells through several mechanisms including but not limited to enhanced immune-reactivity of prolactin and adverse effects of transforming growth factor-beta 1 and epidermal growth factor on the ductal cells [ 13 , 30 , 31 ]. Evidence from animal studies shows changes in the expressions of aquaporin-4 and aquaporin-5 in pregnancy and these studies suggest that these alterations may instigate altered lacrimal gland secretion and eventually result in dry eye symptoms [ 29 ].…”

Section: Resultsmentioning

confidence: 99%

Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

Asiedu¹,

Kyei

Adanusa

et al. 2021

PLoS ONE

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The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital. Clinical dry eye tests were performed along with the administration of a symptom questionnaire. Frequencies, chi-square analysis and logistic regression analyses were conducted to determine the frequency of dry eye disease, its clinical subtypes and associated factors. The prevalence of dry eye disease among the cohort of pregnant women was 82/201 (40.8% 95% confidence interval 34.3%-47.3%). Among the 82 pregnant women with dry eye disease, the frequencies of the clinical subtypes of dry eye were: evaporative dry eye [15/82(18.3%; 95% CI, 12.2%–25.2%)], aqueous deficient dry eye [10/82(12.2.%; 95% CI, 7.3%–18.3)], mixed dry eye [6/82(7.3%; 95% CI, 3.7%–11.0%)], and unclassified dry eye [51/82(62.2%; 95% CI, 52.4%–72.0%)]. Binary logistic regression analysis showed that the following factors were not significantly associated with dry eye: age, BMI, lipid profile, prolactin level, testosterone level, ocular protection index and blink rate. Only gestational age was significantly associated with dry eye disease in pregnancy. In conclusion, the current study showed that dry eye disease occurs frequently in pregnant women ranging from the first to the third trimester and it is associated with increasing gestational age. The evaporative dry eye was more common compared to the aqueous deficient dry eye, but most dry eye could not be classified.

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Contact lens wear in pregnancy

Cited by 9 publications

References 21 publications

Ophthalmic associations in pregnancy

Ophthalmic associations in pregnancy

Oestrogen-induced changes in biomechanics in the cornea as a possible reason for keratectasia

Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study

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