Contact Transscleral Diode Cyclophotocoagulation for Refractory Glaucoma

Threlkeld, Anisa B.; Johnson, Maribeth H.

doi:10.1097/00061198-199902000-00003

Cited by 57 publications

(50 citation statements)

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“…[1][2][3] To the best of our knowledge, there were two reported cases of scleral perforation due to DLTSC in the published literature. 10,11 The case reported by Gaasterland and Pollack 9 was thought to be due to the sharp edge of the probe cutting conjunctival vessels and causing bleeding.…”

Section: Commentmentioning

confidence: 99%

“…[1][2][3] Complications, such as uveitis, pupillary distortion, conjunctival burns, hyphema, chronic hypotony, cystoid macular oedema, retinal detachment, and phthisis bulbi, have been reported. 1,[4][5][6][7][8] Two cases of scleral perforation requiring suturing were described in the published literature.…”

Section: Sir Scleral Perforation Following Diode Laser Trans-scleralmentioning

confidence: 99%

“…Polymerase chain reaction (PCR) for microsporidia was performed using primers capable of identifying several Enterocytozoon and Encephalitozoon species of microsporidia. 3 A single B270 base pair fragment was observed on agarose gel electrophoresis and ethidium bromide staining of the PCR amplified patient sample (Figure 2b). Topical steroids were discontinued and he was treated with topical 0.3% ciprofloxacin eight times daily along with topical lubricants.…”

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Scleral perforation following diode laser trans-scleral cyclophotocoagulation

Kwong

Tham

Leung

et al. 2005

Eye

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microsporidia spores, which were confirmed by 1% acid-fast stain. Polymerase chain reaction (PCR) for microsporidia was performed using primers capable of identifying several Enterocytozoon and Encephalitozoon species of microsporidia. 3 A single B270 base pair fragment was observed on agarose gel electrophoresis and ethidium bromide staining of the PCR amplified patient sample (Figure 2b). Topical steroids were discontinued and he was treated with topical 0.3% ciprofloxacin eight times daily along with topical lubricants. After 10 days, all his lesions had disappeared (Figure 1b). The patient was seronegative for HIV by ELISA test.Bilateral punctate epithelial keratopathy and conjunctivitis has been described in immunocompromised 1,2 and more recently in immunocompetent patients as well. 4,5 Previously described risk factors like trauma, contact lens wear, prior refractive surgery or exposure to contaminated water were absent in our patient. The only possible associated risk in this case was the use of topical steroids, leading to a localized immunosuppressed state, resulting in secondary infection by microsporidia. In our patient, diagnostic debridement probably debulked the epithelium of the load of organisms and hastened resolution. Contrary to belief that debridement worsens the infection by driving the organisms into the stroma; we found that debridement actually hastens resolution. 2 CommentTo the best of our knowledge, this is the first report of keratoconjunctivitis caused by microsporidia in a corneal graft. As a result of local immunosuppression, this infection can occur in patients who have been grafted, which has not previously been described. The differential diagnosis of microsporidial keratitis should be considered in this subset of patients presenting with typical features of multiple epithelial lesions in the cornea.

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Section: Commentmentioning

confidence: 99%

Section: Sir Scleral Perforation Following Diode Laser Trans-scleralmentioning

confidence: 99%

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Scleral perforation following diode laser trans-scleral cyclophotocoagulation

Kwong

Tham

Leung

et al. 2005

Eye

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“…Cyclodestructive procedures such as transcleral cyclophotocoagulation is successful in achieving symptom control in combination with topical steroids and cycloplegia, albeit with risk of hypotony and phthisis. 12 Additional intravitreal anti-VEGF has also been shown to be a useful adjunct in producing rapid pain relief in refractory neovascular glaucoma. 13 Long-term outcomes and the prognosis of eyes treated with the latest approaches in the management of neovascular glaucoma are lacking from recent literature.…”

Section: Table 1: Clinical Experiencesmentioning

confidence: 99%

Reversing the Rubeotic Rampage – Current Approaches in the Management of Neovascular Glaucoma

Rodrigues¹,

Ks²

2016

European Ophthalmic Review

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Neovascular glaucoma is a sight-threatening condition, and can rapidly progress from rubeosis with normal intraocular pressure (IOP), to secondary open-angle glaucoma with raised IOP and finally secondary angle-closure glaucoma with uncontrolled IOP. Early detection and aggressive management with panretinal photocoagulation, intravitreal anti-vascular endothelial growth factor (VEGF), topical aqueous suppressants and valved glaucoma drainage surgery can reduce risk of significant visual loss secondary to neovascular glaucoma. This editorial explores some simple measures that can increase surgical success rates and minimise complications. KeywordsNeovascular glaucoma, rubeosis, anti-vascular endothelial growth factor, tube surgery Disclosure: Ian A Rodrigues and K Sheng Lim have no disclosures or conflicts of interest relevant to this article to declare. No funding was received in the publication of this article. This article is a short opinion piece and has not been submitted to external peer reviewers but was reviewed by the advisory board before publication.Open Access: This article is published under the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, adaptation, and reproduction provided the original author(s) and source are given appropriate credit.

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“…2,3 Bhola reported the serious complications of TCDLC, staphyloma and scleral thinning. All three eyes in his series had pathology, previous radiotherapy, or previous surgery before TCDLC.…”

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